Grants for December 2012

Federal Awards ($100,000 and above)

December 2012 Grant Awards

Ariizumi, Kiyoshi, NIH, DC-HIL in Cutaneous Immunity, $354,173; Babb, Tony, NIH, Dyspnea on Exertion in Obesity: Effects of Exercise Training and Weight Loss, $386,659; Bibb, James, NIH, Novel Signal Transduction Mechanisms in Learning and Memory, $354,173; Browning, Jeffrey, NIH, Role of Mitochondrial Dysfunction in Non-Alcoholic Fatty Liver Disease, $413,042; Burgess, Shawn, NIH, Factors Controlling Metabolic Flux in Liver by NMR Isotopomer Analysis, $345,825.

Cannon, Carolyn, Washington Univ. in St. Louis/NIH, Integrated Nanosystems for Diagnosis and Therapy, $298,352; Chen, Chuo, NIH, Asymmetric Synthesis of Biologically Active Marine Natural Products, $299,820; Chen, Zhijian, NIH, Mechanisms of Protein Kinase Activation by Ubiquitin in NF-kB Pathways, $307,665; Dewey, Richard, NIH, Clinical Center for Neuroprotection in Parkinson’s Disease, $114,184; Greene, Robert, NIH, Glial Control of CNS State-Related Activity, $313,031.

Hall, Christiana, Univ. of Cincinnati/NIH, Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH), $106,095; Hall, Christiana, Univ. of Cincinnati/NIH, Spot Sign for Predicting and Treating ICH Growth Study (STOP-IT), $18,624; Hall, Christiana, Univ. of Virginia/NIH, Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial, $366,934; Hsia, Connie, NIH, Nanoparticle Drug Delivery in Post-Pneumonectomy Compensatory Lung Growth, $612,251; Kramer, Helmut, NIH, Genetics of Endocytic Trafficking in Drosophila Eye, $286,200; Lin, Rueyling, NIH, Transcriptional Regulation by Wnt Effector POP-1, $285,055.

McAdams, Carrie, NIH, Neurobiology of Social Thinking in Anorexia, $171,468; Morrison, Sean, NIH, Stem Cells in Peripheral Nervous System Development, $306,771; Phillips, Margaret, NIH, Lead Optimization of DHODH Inhibitors for Malaria, $636,297.

Ross, Elliott,
NIH, G Protein-Coupled Receptors - Structure and Regulation, $357,750; Seemann, Joachim, NIH, Cell Cycle Regulation of Golgi Membrane Dynamics, $286,200; Shetgiri, Rashmi, NIH, Community-Based Prevention of Youth Violence in Latinos, $126,626; Sperandio, Vanessa, NIH, Quorum Sensing Regulation of EHEC Virulence Genes, $429,302; Zigman, Jeffrey, NIH, Ghrelin's Role in Mood, $354,173.

Non-Federal Awards ($50,000 and above)

Abrams, John, CPRIT, Deconstructing Oncogenic Activity of p53 Mutations, $270,154; Amatruda, James, CPRIT, Identification of Novel Targets for Therapy of Pediatric Germ Cell Tumors, $216,601; Amatruda, James, Hyundai Motor America, Identification of Small Molecule BMP Agonists for Therapy of Childhood Cancers, $50,000; Bachoo, Robert, CPRIT, Unraveling Molecular Mechanisms and Biomechanics of Glioblastoma Invasion, $322,949.

Borek, Dominika, American Heart Assn. Southwest, Mapping of Somatic Mitochondrial DNA Mutations in Aging Heart, $70,000; Chen, Zhijian, CPRIT, Biochemical Mechanisms of NF-kB Activation in Cancer Cells, $281,485; Chiang, Cheng-Ming, CPRIT, Arginine Methylation Link to HPV-16-Induced Cervical Cancer, $100,000; Chook, Yuh Min, CPRIT, Mechanisms of CRM1-Mediated Nuclear Export in Cancer, $210,526; Cleaver, Ondine, CPRIT, Lumen Formation During Blood Vessel Angiogenesis, $200,000.

Cobb, Melanie, CPRIT, Dependence of Small Cell Lung Cancer on Basic Helix-Loop-Helix Transcription Factors Ascl1 and NeuroD1, $411,605; Conrad, Nicholas, CPRIT, Posttranscriptional Regulation of Noncoding RNAs Involved in Epigenetic Regulation of Gene Expression, $100,000; DeMartino, George, CPRIT, Small Molecule Inhibitors of Proteasome Assembly: New Strategy for Cancer Therapy, $100,000.

Gao, Jinming, CPRIT, Turn ON Tumor Contrast for Surgical Resection of Head and Neck Cancers, $321,752; Hofmann, Sandra, CPRIT, Protein Palmitoyltransferases as Novel Therapeutic Targets for Acquired Lung Cancer Vulnerabilities, $100,000; Janowski, Bethany, CPRIT, Regulation of Cyclooxygenase-2 (COX-2) Expression by Noncoding RNAs in Cancer, $210,526; Jiang, Qiu-Xing, CPRIT, Enabling Structure Determination of Functional Human Telomerase Holoenzyme, $224,688.

Kohler, Jennifer, CPRIT, Role of ST6GALNAC5's Sialoside Products in Breast Cancer Metastasis to the Brain, $179,908; Mao, Weihua, CPRIT, Personalized Online Adaptive Radiation Therapy, $420,401; McCulley, James, Research to Prevent Blindness, RPB Unrestricted Research Grant - 2013, $110,000; Mirzaei, Hamid, CPRIT, Develop Cutting-Edge Proteomics Core Facility Based on High Resolution, High Accuracy Mass Spectrometry and High Throughput, Web-Based Bioinformatics Technology, $830,000.

Parada, Luis, CPRIT, Functional and Structural Characterization of Small Chemical Compounds that Arrest Glioma Stem Cell Growth With High Activity and Specificity, $499,725; Russell, David, Clayton Fndtn. for Research, Serum Oxysterols as Biomarkers of Disease, $300,000; Shay, Jerry (S. Singel, Fellow), Susan G. Komen for the Cure, Identify Key Genes in Breast Cancer Genome as Biomarkers of Chemosensitivity or Prognosis, $60,000.

Ward, Sally, UT Dallas/CPRIT, Subcellular Trafficking Studies of HER2 and Anti-HER2 Antibodies; Subawd 110397, $153,095; Ward, Sally, CPRIT, Targeting HER2 for Cancer Therapy, $415,054. Wright, Woodring, CPRIT, Validation of Factors of Telomerase Action (Assembly, Modification, Recruitment, Activation): Potential Targets for Telomerase Inhibition Therapy, $333,920; Yin, Helen, American Heart Assn. Southwest, Estrogen Regulates PIP2 by the Non-Nuclear Pathway to Protect the Endothelium, $70,000.