Janine Prange-Kiel, PhD

Assistant Professor
Cell Biology
Graduate Program: Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-2570
Office Fax: 214-648-8694

janine.prange-kiel@utsouthwestern.edu

Research Interests

Effects of estradiol and synaptic plasticity
Regulation of hippocampal estradiol synthesis
Steroids in the brain

Publications

Featured
Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. , Biology of reproduction , September 2001; (65/3):928-35

Featured
Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. , Biology of reproduction , September 2001; (65/3):928-35

Featured
Hippocampal synapses depend on hippocampal estrogen synthesis.

Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, Prange-Kiel J, Naumann T, Jarry H, Frotscher M, Rune GM. , Journal of Neuroscience , June 2004; (24/26):5913-21

Featured
Median raphe mediates estrogenic effects to the hippocampus in female rats.

Prange-Kiel J, Rune GM, Leranth C. , European Journal of Neuroscience , January 2004; (19/2):309-17

Featured
Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis.

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM. , Journal of Cell Biology , February 2008; (180/2):417-26

Featured
Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons.

Prange-Kiel J, Fester L, Zhou L, Lauke H, Carretero J, Rune GM. , Hippocampus , 2006; (16/5):464-71

Featured
Para/autocrine regulation of estrogen receptors in hippocampal neurons.

Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. , Hippocampus , 2003; (13/2):226-34

Oestrogen synthesis in the hippocampus: role in axon outgrowth

von Schassen C, Fester L, Prange-Kiel J, Lohse C, Huber C, Boettner M, Rune GM , Journal of Neuroendocrinology , November 2006; (18/11):847-56

Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis.

Fester L, Ribeiro-Gouveia V, Prange-Kiel J, von Schassen C, Bottner M, Jarry H, Rune GM , Journal of Neurochemistry , May 2006; (97/4):1136-44

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estradiol synthesis

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM , Journal of Cell Biology , January 2008; (180/2):417-26

Honors/Awards

Alzheimer’s Disease Research Award

Pilot grant by the Friends of the Alzheimer’s Disease Center (2009)

Fellowship of the German Research Foundation

(2002)

Professional Associations/Affiliations

Anatomische Gesellschaft

Endocrine Society

Neurowissenschaftliche Gesellschaft

Society for Neuroscience