Janine Prange-Kiel, PhD

Assistant Professor
Cell Biology
Graduate Program: Neuroscience

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-2570
Office Fax: 214-648-8694

janine.prange-kiel@utsouthwestern.edu

Research Interests

Effects of estradiol and synaptic plasticity
Regulation of hippocampal estradiol synthesis
Steroids in the brain

Publications

Featured
Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis.

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM. , Journal of Cell Biology , February 2008; (180/2):417-26

Featured
Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons.

Prange-Kiel J, Fester L, Zhou L, Lauke H, Carretero J, Rune GM. , Hippocampus , 2006; (16/5):464-71

Featured
Median raphe mediates estrogenic effects to the hippocampus in female rats.

Prange-Kiel J, Rune GM, Leranth C. , European Journal of Neuroscience , January 2004; (19/2):309-17

Featured
Para/autocrine regulation of estrogen receptors in hippocampal neurons.

Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. , Hippocampus , 2003; (13/2):226-34

Featured
Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. , Biology of reproduction , September 2001; (65/3):928-35

Featured
Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. , Biology of reproduction , September 2001; (65/3):928-35

Featured
Hippocampal synapses depend on hippocampal estrogen synthesis.

Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, Prange-Kiel J, Naumann T, Jarry H, Frotscher M, Rune GM. , Journal of Neuroscience , June 2004; (24/26):5913-21

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estradiol synthesis

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM , Journal of Cell Biology , January 2008; (180/2):417-26

Oestrogen synthesis in the hippocampus: role in axon outgrowth

von Schassen C, Fester L, Prange-Kiel J, Lohse C, Huber C, Boettner M, Rune GM , Journal of Neuroendocrinology , November 2006; (18/11):847-56

Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis.

Fester L, Ribeiro-Gouveia V, Prange-Kiel J, von Schassen C, Bottner M, Jarry H, Rune GM , Journal of Neurochemistry , May 2006; (97/4):1136-44

Honors/Awards

Alzheimer’s Disease Research Award

Pilot grant by the Friends of the Alzheimer’s Disease Center (2009)

Fellowship of the German Research Foundation

(2002)

Professional Associations/Affiliations

Anatomische Gesellschaft

Endocrine Society

Neurowissenschaftliche Gesellschaft

Society for Neuroscience