Research in Radiation Oncology

The Department of Radiation Oncology supports four distinct yet interlinked research tracks, all of which ultimately aim at expediting the delivery of better cancer treatment options to our patients. From clinical trials initiated by our own investigators, to basic science and technical research, we are constantly looking for evidence-based methods to improve the safety and efficacy of radiation treatment, as well as enhance the quality of our patients’ lives.

Research News

Westover featured in NCI blog

Ken Westover, M.D., Ph.D., writes about "The Enzymology of GTP-Competitive RAS Inhibitors" on the National Cancer Institute's RAS blog.

Physicians pioneer the use of stereotactic body radiation for deadly kidney cancer complication

UT Southwestern Medical Center Kidney Cancer Program investigators have published what is believed to be the first reported successful use of stereotactic body radiation therapy for an often deadly complication of kidney cancer. Read more.

CPRIT awards faculty $11.5 million for recruitment and research in brain and bone cancer, biology, and immunotherapy

UT Southwestern Medical Center researchers were awarded more than $7.5 million in research grants to improve diagnostic and therapeutic services and research relating to cancers of the brain, breast, throat, and bone, as well as to improve scientific understanding of cancer biology.

UTSW receives key NCI funding to plan first U.S. Center for Heavy Ion Radiation Therapy Research

The National Cancer Institute (NCI) of the National Institutes of Health awarded UT Southwestern a $1 million planning grant to establish the country’s first National Center for Heavy Ion Radiation Therapy.

Stereotactic body radiation therapy plus chemotherapy improves survival among stage 4 lung cancer patients

A clinical trial that combined the two therapy regimens more than doubled survival rates for certain stage 4 lung cancer patients.

Cancer researchers identify irreversible inhibitor for KRAS gene mutation

UT Southwestern Medical Center cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors.

Blocking DNA repair could improve radiation therapy for brain cancer

UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors called glioblastomas.

Possible world's first: Physicians use CyberKnife to treat vocal cord cancer

Stephen Wiley went from being a life-long cowboy to one of the world’s first patients to have vocal cord cancer treated by the CyberKnife, a robot that destroys tumors with highly precise doses of radiation.