Pediatric endocrinology faculty are involved in both basic and clinical research. The Division of Pediatric Endocrinology works with laboratories in other departments and institutions, providing fellows an opportunity to expand their research interests and learning opportunities.
Basic Science Research
Research within the Division is grouped into several main themes.
- Drs. Soumya Adhikari and Kathryn Sumpter have conducted a pilot study of a powerful anti-inflammatory agent – anakinra – in children with new-onset Type 1 diabetes to see if it might be safely used to prolong the honeymoon period in which some insulin secretion remains. Additional studies are planned with a more powerful related agent.
- Perrin White, M.D., has studied several genetic diseases of steroid hormone biosynthesis and metabolism including the most common forms of congenital adrenal hyperplasia. Recently he has concentrated on translational research including studies of gene expression in white blood cells from children with either Type 1 or Type 2 diabetes mellitus, and a pilot study of a potent anti-inflammatory agent, anakinra, in patients with new-onset Type 1 diabetes.