Research in Molecular Genetics
Learn more about our faculty and their groundbreaking research:
Joseph L. Goldstein, M.D.
SREBP (Sterol Regulatory Element Binding Protein) pathway regulation of cholesterol metabolism at the molecular, cellular, and whole-body levels. For more information about Dr. Goldstein’s research, visit the Brown/Goldstein Lab.
Michael S. Brown, M.D.
SREBP (Sterol Regulatory Element Binding Protein) pathway regulation of cholesterol metabolism at the molecular, cellular, and whole-body levels. For more information about Dr. Brown’s research, visit the Brown/Goldstein Lab.
Joachim Herz, M.D.
Molecular basis of Alzheimer’s disease and atherosclerosis. For more information about Dr. Herz’s research, visit the Herz Lab and the Center for Alzheimer’s and Neurodegenerative Diseases.
Helen H. Hobbs, M.D.
Defining the genetic determinants of plasma lipoprotein levels and cardiovascular risk. Please visit the Eugene McDermott Center for Human Growth and Development for more information.
Jay D. Horton, M.D.
How transcriptional regulators of cholesterol metabolism contribute to the development of steatosis in various disease processes such as diabetes, obesity, and beta-oxidation defects. Please visit the Horton Lab for more information.
Arun Radhakrishnan, Ph.D.
Protein-lipid interactions at membrane interfaces.
Masashi Yanagisawa, M.D., Ph.D.
Molecular genetics of sleep/wake mechanisms.
Sarah Comerford, Ph.D.
Maintenance of organ size in normal and cancerous states.
Y.K. (Yiu Kee) Ho, Ph.D.
Generation of mouse monoclonal antibodies against various proteins involved in cholesterol metabolism.
Jeffrey G. McDonald, Ph.D.
Enzymes that synthesize or break down different types of lipids and their roles in whole body lipid metabolism.
Young-ah Moon, M.D., Ph.D.
Characterizing enzymes involved in microsomal fatty acid elongation and defining the potential roles the products of these enzymes have in regulating lipid homeostasis.