Endocrinology Research

The Division of Endocrinology at UT Southwestern encompasses all aspects of endocrinology. A variety of clinical and basic research efforts are directed by a diverse faculty whose expertise spans the spectrum of endocrine disease. Areas of particular strength include steroid hormone biosynthesis and metabolism, endocrine development, and reproduction.

Perry Bickel, M.D.

Dr. Perry Bickel

Research Profile

INTEREST: How cells and tissues regulate intracellular lipid storage and utilization and its effects on systemic glucose and lipid metabolism.

Jonathan Graff, M.D., Ph.D.

Dr. Jonathan Graff

INTEREST: metabolism (obesity and diabetes) and breast cancer, both of which we model in the mouse. We then translate these basic studies to human clinical trials.

Visit the Graff Lab

Ugis Gruntmanis, M.D.

Dr. Ugis Gruntmanis

Research Profile

INTEREST: Proactive identification of patients sustaining fractures and treatment to prevent future fractures.

Uma Gunasekaran, M.D.

Dr. Uma Gunasekaran

Research Profile

INTEREST: Global diabetes program to improve the lives and health of people with diabetes through patient-centered evidence-based care, education, research, and community partnerships.

Ildiko Lingvay, M.D., M.P.H., M.S.C.S.

Dr. Ildiko Lingvay

Research Profile

INTEREST: improving lives of diabetes and obesity patients through understanding of pathophysiology of disease and development of optimal treatment regimens.

David G. McFadden, M.D., Ph.D.

Dr. David McFadden

Research Profile

INTEREST: chemical and genetic approaches to identify new targets for therapy for small cell lung cancer, thyroid cancer and pediatric sarcomas. The lab uses genetically-engineered mouse cancer models and human cancer cell lines as model systems.

Visit the McFadden Lab

Luigi Meneghini, M.D.

Dr. Luigi Meneghini

Research Profile

INTEREST: Global diabetes program to improve the lives and health of people with diabetes through patient-centered evidence-based care, education, research, and community partnerships.

Maria Ramos-Roman, M.D.

Dr. Maria Ramos-Romans

Research Profile

INTEREST: distinguish endocrine changes during active lactation from delayed maternal metabolic reprogramming apparent after the end of lactation

Dwight Towler, M.D., Ph.D.

Dr. Dwight Towler

Research Profile

INTEREST: endocrine regulation of arterial calcification — key contributor to stroke, heart failure, and lower extremity amputation risk in the settings of diabetes and uremia. Current research emphasizes the role LRP6 and arginine methylation cascades in arteriosclerotic Wnt signaling, Wnt production, and microvesicle metabolism. Endocrinology / Hypothalamic / Touchstone Diabetes.

Christoph Zechner, M.D., Ph.D.

Dr. Christoph Zechner

Research Profile

INTEREST: establishing forward genetic approaches in round worms and mammalian cell lines to identify factors that regulate phosphate homeostasis.