Experimental Therapeutics of Cancer

Advancing "personalized medicine" in cancer care by understanding how gene-related processes lead to cancer, and how genetic variation among individuals affects tumor growth and response to treatment.

The Experimental Therapeutics of Cancer Scientific Program focuses on understanding the molecular events leading to individual human cancers and how the molecular differences between tumors influence their behavior and response to therapy. Further, the Program seeks to understand the role of inter-individual genetic variation in developing and treating cancer and to use this information to provide a rationale basis for developing novel diagnostic prevention and therapeutic strategies.

For more information, contact the co-leaders, David Boothman, Ph.D., John  Minna, M.D., and David Gerber, M.D. 

Program Themes

  • Molecular therapeutic sensitizers 
  • Tumor microenvironment and protein therapy 
  • Imaging and drug delivery
  • Cancer vulnerabilities

How To Get Involved

Uptake of peptide-targeted nanoparticles by H2009 non-small-cell lung cancer
Polymeric Micelle Nanoparticles

The Molecular Therapeutics of Cancer Scientific Program seeks additional physicians and scientists with broad understanding of molecular events leading to human cancers for further collaboration research projects.