Profile Details
Schwarz, Roderich MD
Professor
Biographical Information :
| Name: | Schwarz, Roderich MD |
| Title: | Professor |
| Primary Appointment: | Surgery |
| Affiliations: |
The Harold C. Simmons Comprehensive Cancer Center
|
| Schools: |
Southwestern Medical School |
| Department Title: | Division of Surgical Oncology |
| Email: |
Schwarz
Roderich
MD
|
Clinical Information :
Speciality
Surgical Oncology ,Surgery
Clinical Location
Simmons Comprehensive Cancer Center
Phone
214-645-4673
Address
Simmons Comprehensive Cancer Center
2201 Inwood Rd
Dallas,TX
75390
Clinical Interest
Bile Duct Cancer
Gastric Cancer
Liver Cancer
Pancreatic Cancer
Research Information:
Faculty Research Bio
Dr. Schwarz’ translational research interests focus on experimental combination therapy for pancreatic, hepatobiliary, and gastric cancer. His laboratory-based research has explored the use of antiangiogenic therapy alone or in combination with conventional cytotoxic chemotherapy in vivo. The strategy of combining therapeutic agents that address various targets supporting the cancer progression has led to significant delays of experimental cancer growth, with extension of survival. Currently, the laboratory focuses on mechanisms of cancer cell adhesion, migration, and invasion, that may represent promising targets to enhance anticancer effects in combination therapy with an antiangiogenic component.
Address
UT Southwestern Medical Center at Dallas
5323 Harry Hines Blvd
Dallas,
Texas
75390
Contact:
214-648-5865
Recent Publications
Schwarz, R.E., Smith, D.D. , " Lymph node dissection impact on staging and survival of extrahepatic cholangiocarcinomas, based on U.S. population data. "J. Gastrointest. Surg. ,11(2):158-65 ,February 2007
Konduri, S., Schwarz, R.E. , " Estrogen receptor beta / alpha ratio predicts pancreatic cancer cell response to estrogens and phytoestrogens. "J. Surg. Res. ,140(1):55-66 ,June 2007
Schwarz, R.E. , " Factors influencing change of preoperative treatment intent in patients with gastrointestinal cancer. "World J. Surg. Oncol. ,5(1):32 ,March 2007
Verma, V., Schwarz, R.E. , " Factors influencing perioperative blood transfusions in patients with gastrointestinal cancer. "J. Surg. Res. ,141 (1):97-104 ,July 2007
Schwarz, R.E., Smith, D.D. , " Clinical impact of lymphadenectomy extent in resectable esophageal cancer. "J. Gastrointest. Surgery ,(in press),2007
Significant Publications
Schwarz, R.E., Smith, D.D. , " Clinical impact of lymphadenectomy extent in resectable gastric cancer of advanced stage. "Ann. Surg. Oncol. ,14(2):317-328 ,February 2007
Schwarz, R.E. , " Visceral organ resections combined with synchronous major hepatectomy: examples of safety and feasibility. "HPB J. Internat. Hepato Pancreato Biliary Assoc. ,5(1):27-32 ,2003
Schwarz, R.E., Smith, D.D., Keny, H., Ikle, D.N., Shibata, S.I., Chu, D.Z.J., Pezner, R.D. , " The impact of intraoperative radiation on postoperative and disease-specific outcome after pancreatoduodenectomy for adenocarcinoma: a propensity score analysis. "Am. J. Clin. Oncol. ,26 (1):16-21 ,2003
Schwarz, R.E., Zagala-Nevarez, K. , " Recurrence patterns after radical gastrectomy for gastric cancer: prognostic factors and implications for postoperative adjuvant therapy. "Ann. Surg. Oncol. ,9(4):394-400 ,2002
Schwarz, R.E., Harrison, L.E., Conlon, K.C., Klimstra, D.S., Brennan, M.F. , " The impact of splenectomy on outcome after resection of pancreatic adenocarcinoma. "J. Am. Coll. Surg. ,188:516-521 ,1999
Personal Information:
Faculty Personal Bio
Dr. Roderich Schwarz joined the Department of Surgery at the UT Southwestern Medical School and the Simmons Comprehensive Cancer Center in the middle of 2007, to serve as Professor of Surgery and Chairman of the Division of Surgical Oncology. A native of Germany, he completed his medical training at the Medical School in Hannover, Germany, in 1984, and presented his dissertation with a thesis in experimental hepatopathology in 1985. Until 1989, he was a postdoctoral research fellow at the Pittsburgh Cancer Institute in Pittsburgh, PA, and subsequently underwent residency training in General Surgery in the Department of Surgery at the University of Pittsburgh. In 1994, he started a two-year fellowship training in Surgical Oncology at Memorial Sloan-Kettering Cancer Center in New York, where he has received specialty training for gastrointestinal cancer with Drs. Murray F. Brennan, Alfred M. Cohen, and Leslie H. Blumgart. From 1996 to 2001, he served as Section Head of Upper Gastrointestinal and Pancreatobiliary Surgery at the City of Hope Cancer Center in Los Angeles, California. Subsequently, he led the Pancreatic Cancer Program at the Cancer Institute of New Jersey and Robert Wood Johnson Medical School in New Brunswick, NJ, from 2001 to 2007.
Dr. Schwarz has a special interest in upper gastrointestinal malignancies, including pancreatic, hepatobiliary, and gastric cancer. He has presented numerous talks at national and international meetings, and has authored more than eighty peer reviewed journal articles and several book chapters. His research interests focus on experimental combination therapy for pancreatic and gastric cancer, novel locoregional therapies for liver and bile duct lesions, and minimizing morbidity after major visceral resections.
Dr. Schwarz has taken an active role in the design and implementation of experimental multidisciplinary treatment protocols for gastrointestinal cancer at UTSW. Of major interest are: 1. adjuvant combination treatment strategies that incorporate molecular-targeted drugs for growth inhibition and antiangiogenesis with conventional cytotoxic therapy; 2. intraperitoneal treatment with or without surgical cytoreduction; 3. regional intrahepatic chemotherapy after resection / radiofrequency ablation of hepatic metastases. Dr. Schwarz seeks to create a cooperative and productive relationship with physicians who diagnose and treat gastrointestinal cancer. He is available for clinical consultations or direct physician contact at any time.
Medical School
Med Hochschule Hannover, Hannover, Germany (1984)
Residency
University of Pittsburgh Medical Center,General Surgery (1989-1994)
Fellowship
Pittsburgh Cancer Institute,Postdoctural Research Fellowship (1987-1989)
Memorial Sloan-Kettering Cancer Center, NY, NY,Surgical Oncology Fellowship (1994-1996)
Boards
General Surgery
Honors
UMDNJ Robert Wood Johnson Medical School (2006)
Japan Surgical Society (2001)
NIH-K12 Fellow Award (2001)
Society of Surgical Oncology (1995)
Deutsche Forschungsgemeinschaft (1989)
Language
English