Jonathan Weissler, MD

Professor
Endowed Title: James M. Collins Center for Biomedical Research
James M. Collins Professorship in Biomedical Research
Internal Medicine
Graduate Program: Immunology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

jonathan.weissler@utsouthwestern.edu

Biography

1993-4 President, American Federation for Clinical Research; 1990 NIH Special Review Cmte "National Cooperative Drug Discovery Groups in AIDS", 1993 NIH Review Cmte. "Collaborative Projects in Minority Health", 1996 NIH SCOR Review Panel "Cellular and Molecular Mechanisms of Asthma", 1996 Review Panel American Lung Association "Asthma Research Centers", 1994-98 Editor, Journal of Investigative Medicine, 1998-2003 Editorial Board, American Journal of Respiratory Cell and Molecular Biology, 1998-99 Chair, Program Planning Cmte (Allergy, Immunology, and Inflammation) American Thoracic Society Annual Meeting, 1999-2000 President, Association of Pulmonary and Critical Care Medicine Program Directors, 2000-2 Publication Policy Cmte American Thoracic Society,2001 Reviewer,Minority Health Research and Education Grant Program,Texas Higher Education Coordinating Board, 2003-2010 Scientific Advisory Board Lovelace Respiratory Research Institute, Albuquerque New Mexico; 2003-2006 Board of Directors, Alliance for Academic Internal Medicine; 2004-2005 President,Association of Subspecialty Professors; 2003-11 Listed in Americas Top Doctors; 2003-11 Best Doctors in America; Chief Division of Pulmonary and Critical Care Medicine UT Southwestern 1996-2007; Interim Chief of Medical Service Parkland Memorial Hospital 2010-11; Chief of Medicine, UT Southwestern University Hospitals 2006-Present

Education

Graduate SchoolNew York University (1979)
UndergraduateUniversity of Michigan-Ann Arbor (1975)

Research Interests

Idiopathic Pulmonary Fibrosis
Severe Asthma
Transcriptional Regulation of Surfactant proteins

Publications

Featured
Alloantigen-induced immunoglobulin production in human lung: Differential effect of accessory cell subpopulations on IgG synthesis

Wilkes D.S. and J.C. Weissler , Am J Resp Cell Mol Biol , November 1994; (10):339-46

Featured
Separation of potent and poorly functional human lung accessory cells based on autofluorescence

Nicod L., M.F. Lipscomb, G.B. Toews, and J.C. Weissler , J. Leukoc. Biol , May 1989; (45):458-65

Featured
PLAGL-2, a zinc finger protein,transactivates the surfactant protein-C promoter

M.C. Yang, J.C. Weissler, L.S. Terada, F. Deng, and Y.S. Yang , Am J Respir Cell Mol Biol , January 2005; (32(1)):35-43

Featured
Enhanced accessory cell function by alveolar macrophages from patients infected with the human immunodeficiency virus

Twigg H. L., M.F. Lipscomb, B. Yoffe, D. Barbaro, and J.C. Weissler , Am. J Respir Cell Mol Biol , January 1989; (1):391-400

Featured
Effect of interstitial lung disease macrophages on T cell signal transduction

Weissler J.C., Mendelson C., Moya F., and W.C. Yarbrough , Am J Respir Crit Care Med , 1994; (149):191-196

PLAGL-2 expression induced epithelium damages in emphysema

Yang, Y.S., Yang M.C.,Guo M, and J.C. Weissler , Am J Phys (Lung) , September 2009; (297):455-466

Pleiomorphic Adenoma Gene-like 2 Expression Is Associated with the Development of Lung Adenocarcinoma and Emphysema

Yih-Sheng Yang, Meng-Chun W. Yang, and J.C. Weissler , Lung Cancer , Oct 2011; (72(2)):in press

Adult-onset pulmonary fibrosis caused by mutations in telomerase

Tsakiri,K.,Cronkhite,J.,Kuan,P.,Xing,C.,Raghu,G.,Weissler J.C., Rosenblatt R.,Shay,J.,Garcia, C.K. , PNAS , May 2007; (Vol 104, No. 18):7552-7557

TTF-1/TAP26 Complex Differentially Modulates Surfactant Protein-B (SP-B) and -C (SP-C) Promoters in Lung Cells

Yang, M.C., Guo,Y, Liu, C, Deng, F, Weissler J.C., and Y.S. Yang , Biochem and Biophys Res Communications , June 2006; (344 (2)):484-490

Nuclear relocation of PLAGL2 modulates gene activity in hypoxic lung cells: a mechanism in maintaining SP-C expression

Guo,Y., Yang,M.C., Weissler, J.C., and Y.S. Yang , Biochem and Biophys Res Communications , August 2007; (360 (3)):659-665

Professional Associations/Affiliations

American College of Physicians

American Thoracic Society

Dallas County Medical Society

Texas Medical Association