Tissue Transplantation and Medical Indications 

Tissue donation includes bone, tendons, cartilage, connective tissue, skin, corneas, sclera, heart for valves, and vessels. These grafts are used for a variety of surgical applications. A tissue transplant in hospitals, day surgery centers, and dental offices occurs nearly every day. These surgeries often are not adequately appreciated as life changing, life enhancing, and in the case of skin for burn patients even life-saving events which are donor dependent. The following table illustrates some of the multiple clinical applications of allograft tissue.

SURGICAL SPECIALTY TRANSPLANTABLE TISSUES INDICATIONS TYPICAL APPLICATIONS BENEFIT TO PATIENTS

OCULAR

Ophthalmology

Cornea

Keratpathy

Keratoconus

Dystropathy

Corneal scars and ulcers

Replace diseased or damaged cornea

Prevents blindness

Restores vision

 

 

Sclera

Glaucoma

Trauma

Congenital deformities

Sclera patch graft

Repair eyelid

Reinforce wall of eye

Preserves structure

Repairs defects

Aid in intraocular, pressure stabilization

 

Fascia

Lidtonis

Eye lid repair

Improves lid function and appearance

MUSCULOSKELETAL – BONE AND CONNECTIVE TISSUE

Orthopaedics

Podiatry

Dentistry

Plastic Surgery

Oral-Maxillofacial

Long Bones

Iliac Crest

Acetabulum

Rib

Tumors

Trauma

Congenital Deformities

Degenerative Diseases

Fractures

Reconstruction and repair

Hip revision

Spinal fusion

Jaw and facial defect surgery

Dental surgery

Bone replacement

Prevents amputation

Accelerates and promotes healing

Restores mobility

Reduces pain and possibility of nerve damage

Restores normal appearance

 

Patellar Tendon

Achilles Tendon

Cartilage

Fascia Lata

Congenital Deformities

Traumatic injury

Tendon replacement and/or repair

Use as rotator cuff

Reconstruction in traumatic

Facial injuries/deformity

Restores mobility

Restores independence in activities of daily living

Restores normal appearance

SKIN

General Surgery

Trauma

Burn Surgery

Skin

Burns

Soft tissue wounds

Skin grafts on severe burn injuries

Grafts for slow or non-healing wounds

Promotes healing

Protects underlying tissues

Prevents loss of bodily fluids

Provides protection barrier against infection

Relieves pain

VASCULAR

Thorasic & Vascular

Heart Valves

Valvular Disease

Aortic and pulmonary valve replacement

Reduces long-term anticoagulant therapy

Allows children to grow into graft (reduces need for second surgery)

 

Saphenous Veins

Bypass Surgery

CABG (Coronary artery bypass surgery)

Below the knee vascularization

Restores cardiac function

Prevents amputation

NEUROSURGERY

Neurosurgery

Pericardium

Trauma

Neurology Hemorrhage

Neurosurgery

Protective covering

Structural preservation

UROLOGY

Urology

Fascia

Bladder repair and suspension

Bladder prolapse

Improved function and pain reduction