The Pediatric Surgery service is based at Children's Medical Center with most of the neonatal patients cared for in the Special Care Nursery of Parkland Hospital, which is contiguous with Children's. The Pediatric Surgery Service at Children's has five full-time UT Southwestern Medical Center faculty and seven clinical faculty.

Clinical activities of the full-time faculty include special interests in the treatment of children with vascular disease, tumors, a need for advanced minimally invasive surgical procedures, and those with serious injuries.