Open physician-scientist positions are listed below; please visit Human Resources for other career opportunities at UT Southwestern Medical Center.


Academic Pediatric Pathologist

The Department of Pathology is seeking an academic pediatric surgical pathologist at Assistant or Associate Professor level. The position requires experience in all facets of pediatric and perinatal pathology and demonstrated accomplishments in research. Preference will be given to candidates with interest/additional training or experience in pediatric GI or oncologic pathology. The applicant must have an M.D., M.D./Ph.D. or D.O., be certified by the American Board of Pathology in Anatomic/Clinical Pathology or Anatomic Pathology, be board eligible or certified in Pediatric Pathology, and have or be eligible for a Texas medical license.

The primary clinical responsibilities are at the 559-bed Children’s Medical Center Dallas, with 8,000 surgical specimens, 150 perinatal and pediatric autopsies, and 1,500 placentas annually. In addition to patient care activities, the incumbent will be expected to participate in Pathology Department and institutional activities, medical student and house staff teaching and mentoring, and to develop or continue their research program. Outstanding opportunities for collaborative, translational research are available with members of both basic science and clinical departments throughout UT Southwestern. Competitive salary and start-up will be provided. Applicants should send a cover letter, curriculum vitae, brief research statement, and three letters of reference to:

James S. Malter, M.D.
Department of Pathology
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9072

UT Southwestern Medical Center is an Affirmative Action/Equal Opportunity Employer. Women, minorities, veterans, and individuals with disabilities are encouraged to apply. 

Postdoctoral Researchers

Tumor Suppressors in Cancer (265)

Two postdoctoral research positions are available as of November 15, 2012, on NIH-funded projects for highly motivated, creative, and accomplished Ph.D.s in a related discipline, with experience in cancer research to join a growing lab in the Department of Pathology at UT Southwestern. Ideal candidates will have a track record of leading projects to publication. Position responsibilities include directing independent projects in a multidisciplinary setting and mentoring junior lab members. The selected candidates will be expected to apply for independent fellowship funding.

Breast Cancer Research

This position will focus on studying the role of retinoblastoma tumor suppressor pathway (RB, p16ink4a, and cyclin D1) in breast cancer. Specific emphasis will be placed on the role of RB loss in disease progression and therapeutic response. This work will incorporate the use of cell culture, animal models, and clinical specimens.

Tumor Suppressors in Cancer Research

This position will focus on deciphering mechanisms through which the tumor suppressors function in the control of cell cycle progression and tumor suppression. These studies will use genetically engineered mouse models to specifically interrogate key processes coordinated by RB, p53, and additional tumor suppressors.

Candidates should send a CV, the names of several references, and a brief research statement to:

Erik Knudsen, Ph.D.
UT Southwestern Medical Center
Department of Pathology
5323 Harry Hines Blvd.
Dallas, Texas 75390-9072

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer

Prostate Cancer Epigenetics and Genomics (368)

Two postdoctoral positions are currently available in the Research Group of Ram Mani, Ph.D., in the Pathology Department. We are seeking highly motivated candidates with a background in cancer biology, epigenetics, chromatin biology, DNA repair and/or genomics. The research focus is in the area of prostate cancer epigenetics and genomics. We are interested in understanding the epigenetic signatures of prostate cancer development with an emphasis on mechanisms of treatment resistance. We are also interested in studying the molecules and pathways underlying the formation of genomic rearrangements in cancer, with a major focus on ETS gene fusions. We employ state-of-the-art molecular biology and cell biology tools, next-generation sequencing methods like ChIP-Seq, and custom capture sequencing, in addition to in vivo experiments, to address these scientific questions. For additional information on our research, see Science (2009 #PMID: 19933109), Cancer Cell (2010 #PMID:20478527), Nature Reviews Genetics (2010 #PMID:21045868), Cancer Research (2011 #PMID:21676887).

Applicants must hold a Ph.D., and/or M.D. in biological sciences or other related disciplines and have a strong publication record. Experience with bioinformatics is a plus.

Interested candidates should send a cover letter, CV, description of research accomplishment and three letters of reference to:

Ram S. Mani, Ph.D.
Assistant Professor
Department of Pathology
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75235-9072


Computational Biologist I

The laboratories of Erik Knudsen, Ph.D., and Agnes Witkiewicz, M.D., currently have a position open for a highly motivated Computational Biologist I. Candidates with experience with gene expression and next generation analysis are encouraged to apply through Career Opportunities and Employment Information under Research & Laboratory Support. Job ID 507149.

UT Southwestern Medical Center is an Equal Opportunity, Affirmative Action Employer