Center for Autophagy Research

The Center for Autophagy Research at UT Southwestern Medical Center is designed to foster a collaborative interdisciplinary environment for promoting cutting-edge research in the field of autophagy.  

Autophagy is a fundamental cell biology process that is important for many aspects of normal development and physiology. It is also important in protection against a wide range of diseases, including cancer, aging, neurodegenerative disorders, infectious diseases, inflammatory disorders, and metabolic diseases. Scientists within the Center for Autophagy Research have played a key role in identifying molecules essential for autophagy, in elucidating the biochemical regulation of autophagy, and in using genetic approaches to unravel the functions of autophagy in normal physiology and disease prevention.

Our mission is to further develop state-of-the art, innovative, research programs in the biochemistry, structural biology, cell biology, genetics, pharmacology, developmental biology, and physiological or pathophysicological roles of autophagy. Such programs will lead to significant advances in understanding the basic mechanisms of autophagy and its roles in health and disease.