A once-daily combination treatment for those with uncontrolled Type 2 diabetes amplifies the treatment’s effects – lowering both weight and the number of hypoglycemic events. The combo treatment also leads to greater medication adherence and improves quality of life and glucose control.

These findings, from a clinical trial led by UT Southwestern, were based on research comparing a once-daily combination treatment – basal insulin and a glucagon-like peptide-1 receptor agonist shot given at the same time each day – against more frequent doses of basal-bolus insulin.

It is the first such report evaluating the different regimens in people with highly elevated blood sugar levels (hemoglobin A1c), which elevates the risk of complications.

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