Dinesh Rakheja, MD

Assistant Professor
Pathology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-456-2322
Office Fax: 214-456-0779

dinesh.rakheja@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Education

FellowshipUT Southwestern / Children's Medical Center, Pediatric Pathology (2006)
ResidencyUT Southwestern Medical Center at Dallas, Pathology (2003)
ResidencyGB Plant Hospital, Pathology (1999)
ResidencyMaulana Azad Hospitals, Pathology (1997)
Medical SchoolAll India Institute of Medical Sciences (1993)

Publications

Featured
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.

Choi C, Ganji SK, Deberardinis RJ, Hatanpaa KJ, Rakheja D, Kovacs Z, Yang XL, Mashimo T, Raisanen JM, Marin-Valencia I, Pascual JM, Madden CJ, Mickey BE, Malloy CM, Bachoo RM, Maher EA, Nature medicine, 2012 Jan;

Featured
Mutation in the type IB bone morphogenetic protein receptor alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish.

Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L, Margraf L, Rakheja D, Amatruda JF, Proceedings of the National Academy of Sciences of the United States of America, 2011 Jul; :13153-8

Featured
Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours.

Fustino N, Rakheja D, Ateek CS, Neumann JC, Amatruda JF, International journal of andrology, 2011 Aug; 34 (4 Pt 2):e218-33

Featured
High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.

Rakheja D, Konoplev S, Su M, Wheeler D, Muzny DM, Ruvolo VR, Collins R, Karandikar NJ, Andreeff M, Medeiros LJ, Chen W, British journal of haematology, 2011 Apr; :125-8

Featured
Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate.

Rakheja D, Boriack RL, Mitui M, Khokhar S, Holt SA, Kapur P, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2011 Apr; 32 (2):325-33

Featured
CLN3P, the Batten's disease protein, is a novel palmitoyl-protein Delta-9 desaturase.

Narayan SB, Rakheja D, Tan L, Pastor JV, Bennett MJ, Annals of neurology, 2006 Nov; 60 (5):570-7

Featured
Evidence for fatty acid oxidation in human placenta, and the relationship of fatty acid oxidation enzyme activities with gestational age.

Rakheja D, Bennett MJ, Foster BM, Domiati-Saad R, Rogers BB, Placenta, 2002 May; 23 (5):447-50

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.

Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF, Disease models & mechanisms, 2012 Jan; 5 (1):95-106

Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.

Heaphy CM, Subhawong AP, Hong SM, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih IeM, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, Taube JM, Rakheja D, Kurman RJ, Wu TC, Roden RB, Argani P, De Marzo AM, Terracciano L, Torbenson M, Meeker AK, The American journal of pathology, 2011 Oct; 179 (4):1608-15

The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis.

Peng A, Ye T, Rakheja D, Tu Y, Wang T, Du Y, Zhou JK, Vaziri ND, Hu Z, Mohan C, Zhou XJ, Kidney international, 2011 May; :601-11

Books

Focus on Cholesterol Research (Cholesterol biosynthetic disorders: a review)

Rakheja D, Rogers BB, Bennett MJ, Nova Publications (Hauppauge, NY) 2006

Tietz's Applied Laboratory Medicine (The "fussy" neonate)

Jones PM, Rakheja D, Wiley-Interscience, John Wiley & Sons Inc. (Hoboken, NJ) 2007

Quick Guide to Organic Acid Interpretation

Jones PM, Rakheja D, American Association for Clinical Chemistry Press (Washington, DC) 2011

Tietz's Applied Laboratory Medicine (The "sleepy" neonate)

Rakheja D, Jones PM, Wiley-Interscience, John Wiley & Sons Inc. (Hoboken, NJ) 2007

Silva's Diagnostic Renal Pathology (Glomerular diseases associated with nephritic syndrome and/or rapidly progressive glomerulonephritis)

Rogers T, Rakheja D, Zhou XJ, Cambridge University Press (New York, NY) 2009

Silva's Diagnostic Renal Pathology (The aging kidney)

Zhou XJ, Rakheja D, Silva FG, Cambridge University Press (New York, NY) 2009

Honors/Awards

Pediatric Pathology Visiting Scholar Award, Children’s Hospital Boston, Harvard Medical School

(2006)

College of American Pathologists Foundation (CAPF) Scholar

(2004)

Harry B. Neustein Memorial Award, Society for Pediatric Pathology

(2004)

Travel Award for junior investigators, Society for Inherited Metabolic Disorders

(2004)

F Stephen Vogel Award, United States and Canadian Academy of Pathology

(2003)