Science in 60+: Stimulating Change

Published on: March 30, 2026 By: Staff Reports

For many people living with depression, medication and therapy can be life-changing – but more than 30% of patients experience treatment-resistant depression, where symptoms persist despite multiple approaches.

Deep brain stimulation (DBS) is being studied as a possible new option to provide effective, lasting relief for patients with treatment-resistant depression. Frederick Hitti, M.D., Ph.D., Assistant Professor of Neurological Surgery and Psychiatry, explains how it works.

Take a deeper dive.