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TBK1 is hyperactivated by VHL loss or hypoxia and may be a therapeutic target for kidney cancer

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ZHX2 activates NF-kB signaling in kidney cancer

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Genome-wide Screening Identifies SFMBT1 as an Oncogenic Driver in Cancer with VHL Loss

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Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer

Research

Hypoxia is associated with resistance towards radiation and chemotherapy. As tumors grow, they can sense the oxygen tension and reprogram critical pathways that are important for cancer cell survival and therapy resistance. (read more)

Meet the PI 

Qing Zhang, Ph.D.

Publications

Meet the lab