Research

TRUST Funding

Established Investigator Award

Grant ID

RR150010

Active Date

12/01/2014 - 11/30/2019 

Primary Investigator

Robert Mattrey, M.D.

Awarding Institute

Cancer Prevention Research Institute of Texas

Goal

Establish a translational ultrasound research program at the University of Texas, Southwestern, Dallas, TX in cancer.


Idea Award with Special Focus

Grant ID

W81XWH-17-1-0401

Active Date

09/01/2017-08/31/2019

Primary Investigator

Caroline de Gracia Lux, Ph.D.

Awarding Institute

Department of Defense

Goal

To develop a game changing approach for the treatment of acute lymphoblastic leukemia by generating CAR T-cells directly in vivo using microbubbles. To reach this goal, ultrasound-mediated gene delivery and CAR T-cell therapy will be merged to create externally controllable cells aimed at depleting malignant B-cells.

 


2017 Docstars Award

Grant ID

N/A

Award Date

11/06/2017

Primary Investigator

Jacques Lux, Ph.D.

Awarding Institute

The Cary Council

Goal

In recognition and support of promising early-stage research  


Developmental Research Pilot Award to develop preliminary data to support a SPORE application

Grant ID

N/A

Active Date

09/26/2018-09/25/2019

Primary Investigator

Caroline de Gracia Lux, Ph.D.

Awarding Institute

Harold C. Simmons Comprehensive Cancer Center

Goal

To treat hepatocellular carcinoma (HCC) non-invasively by occluding their microvasculature, as in Trans-arterial chemoembolization (TACE), but from within rather than rely on embolizing the feeding artery.  


Children's Cancer Fund Comprehensive Center for Pediatric Oncology Research Award

Grant ID

N/A

Active Date

10/02/2018-10/01/2021

Primary Investigator

Jacques Lux, Ph.D.

Awarding Institute

Children's Cancer Fund

Goal

To improve efficacy and safety of amino acid depletion for acute lymphoblastic leukemia using a translatable nanotechnology.  


 

Completed Funding

Translational Pilot Program Grant

Grant ID

UL1TR001105

Active Date

09/01/2016-08/31/2017

Primary Investigator

Jacques Lux, Ph.D.

Awarding Institute

Center for Translational Medicine (CTM)

Goal

To image reactive oxygen species with ultrasound imaging.