Featured Publications

NPAS4 regulates the transcriptional response of the suprachiasmatic nucleus to light and circadian behavior.

Xu P, Berto S, Kulkarni A, Jeong B, Joseph C, Cox KH, Greenberg ME, Kim TK, Konopka G, Takahashi JS, Neuron 2021 Aug

Importance of circadian timing for aging and longevity.

Acosta-Rodríguez VA, Rijo-Ferreira F, Green CB, Takahashi JS, Nat Commun 2021 05 12 1 2862

Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony.

Shan Y, Abel JH, Li Y, Izumo M, Cox KH, Jeong B, Yoo SH, Olson DP, Doyle FJ, Takahashi JS, Neuron 2020 10 108 1 164-179.e7

Epigenetic inheritance of circadian period in clonal cells.

Li Y, Shan Y, Kilaru GK, Berto S, Wang GZ, Cox KH, Yoo SH, Yang S, Konopka G, Takahashi JS, Elife 2020 05 9

The malaria parasite has an intrinsic clock.

Rijo-Ferreira F, Acosta-Rodriguez VA, Abel JH, Kornblum I, Bento I, Kilaru G, Klerman EB, Mota MM, Takahashi JS, Science 2020 05 368 6492 746-753

Noise-driven cellular heterogeneity in circadian periodicity.

Li Y, Shan Y, Desai RV, Cox KH, Weinberger LS, Takahashi JS, Proc Natl Acad Sci U S A 2020 05 117 19 10350-10356

Sleeping sickness is a circadian disorder.

Rijo-Ferreira F, Carvalho T, Afonso C, Sanches-Vaz M, Costa RM, Figueiredo LM, Takahashi JS Nat Commun 2018 01 9 1 62

Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System.

Acosta-Rodríguez VA, de Groot MHM, Rijo-Ferreira F, Green CB, Takahashi JS Cell Metab. 2017 Jul 26 1 267-277.e2

Transcriptional architecture of the mammalian circadian clock.

Takahashi JS Nat. Rev. Genet. 2016 Dec

Forward-genetics analysis of sleep in randomly mutagenized mice.

Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M Nature 2016 Nov 539 7629 378-383