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Focal Stroke
CD19+ B cells (green) move next to neurons (red) in the infarct region after focal stroke in mice
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Repetitive Hypoxic Preconditioning
Pictorial representation of an anti-inflammatory phenotype in the preconditioned brain (illustration courtesy of C. Johnsen)
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B Cell Recruitment
Following stroke, cortical vessels surrounded by astrocytes endfeet (GFAP) upregulate the chemokine CXCL13 (red) to recruit B cells from the periphery
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In Vitro Stroke Model
Mixed cortical cultures, with neurons identified by MAP2 (red), are exposed to oxygen-glucose deprivation as an in vitro stroke model
Meet the PI
Ann Stowe, Ph.D.
Our Research
The Stowe Lab conducts both bench and clinical research with the goal of deepening the understanding of the etiology of stroke as well as finding better therapies for those who have suffered a stroke.
