Vibrio II

The second pathogenicity island of Vibrio parahaemolyticus contains T3SS2 and is associated with enterotoxicity. Since its discovery, this bacterium has been regarded as an exclusive extracellular bacterium, Recently we have demonstrated that Vibrio parahaemolyticus is actually a facultative intracellular pathogen. The novel understanding of V. parahaemolyticus as an intracellular bacterium compares to a “rediscovery” of this bacterium, which presents itself as a model poised for future studies of T3SS-mediated disruption of intracellular processes. Recently, the putative effectors are being reassessed and have shown that actually contribute to the bacterium’s intracellular lifestyle.