Much of what we study can be thought of as an elaborate chess match between hosts and the pathogens which infect them. Similar to chess there are a variety of pieces on the board (e.g. proteins) with some more valuable/powerful than others like the queen.

In the lab, we are using a variety of methods to identify queens on both the host and pathogen side (Project 1) and how they move of the board including different strategies (Project 1 and 3). Notably, there are corresponding pieces that mirror each other from across the board.

For example, each side has a knight. Notably, pathogens such as viruses often rewire cellular functions via mimicry using stolen host proteins repurposed for infection (Project 3).