Welcome to the Greene Lab

Neural circuits in the mammalian central nervous system, at local and systems levels, undergo changes of state behaviorally reflected as wake and sleep. Wakefulness may be further sub-divided by level of arousal and/or attention, and sleep into rapid eye movement (REM) sleep and non-rapid eye movement (NREM) sleep.

Our lab uses a combination of electrophysiological and molecular techniques to examine functions sub-served by these states at the cellular and circuit levels. Further, our studies characterize mechanisms responsible for pathologies associated with disruption of sleep/wake states: for example, post-traumatic stress disorder, neurodegeneration, failed recovery from traumatic brain injury, and drug addiction.