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Quantitative 3D live cell imaging
Example of cortical actin density in transformed lung cancer cell model (left) and primary melanoma cell (right).
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Causality in molecular pathways
We adopt mathematical methods from econometrics to infer causality between subcellular activities from live cell image data.
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RHOA GEF role in mediating cell motility
Zaritsky, Tseng and colleagues have identified a surprising role for the Rho family GTPases in mediation of cell motility and cell-cell communication.
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Tracking particle movement in dense environments
Roudot et. al., published a new method for heterogeneous particle motion tracking in the intracellular environment.
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Quantification of Cell-to-Cell Morphological Heterogeneity
Bagonis et al. developed a robust, new method for the automated quantification of diverse, filopodia-rich, cellular morphologies such as neuronal growth cones.
