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Cell mechanics orchestrates cell metabolism

Park et al. discovered a mechanism by which epithelial cells adjust glucose metabolism to extracellular matrix stiffness.

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How does cell shape shape cells?

Driscoll et al. publishes u-shape3D, a suite of computational tools to investigate how 3D cellular morphology governs intracellular signaling.

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Step off the brakes to get somewhere

Welf et al. discover the necessity of membrane-actin bond release for cell protrusion initiation.

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SH3BP4 -- the link between adhesion and Akt signaling

Christoph Burckhardt discovers how SH3BP4 mediates integrin endocytosis dependent on Akt activity.

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