Cell mechanics orchestrates cell metabolism

Park et al. discovered a mechanism by which epithelial cells adjust glucose metabolism to extracellular matrix stiffness.


How does cell shape shape cells?

Driscoll et al. publishes u-shape3D, a suite of computational tools to investigate how 3D cellular morphology governs intracellular signaling.


Killer Lamellipodia

Mohan et al. publishes evidence for cell morphology dictating oncogenic proliferation signals.


Coupling discrete and continuous signals

Azoitei, Noh et al. publish work that establishes based on a new biosensor and a novel statistical that microtubule catastrophe events promote activation of the RhoA GEF GEF-H1.


Quantification of Cell-to-Cell Morphological Heterogeneity

Bagonis et al. developed a robust, new method for the automated quantification of diverse, filopodia-rich, cellular morphologies such as neuronal growth cones.

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