Example of cortical actin density in transformed lung cancer cell model (left) and primary melanoma cell (right).
Causality in molecular pathways
We adopt mathematical methods from econometrics to infer causality between subcellular activities from live cell image data.
RHOA GEF role in mediating cell motility
Zaritsky, Tseng and colleagues have identified a surprising role for the Rho family GTPases in mediation of cell motility and cell-cell communication.
Tracking particle movement in dense environments
Roudot et. al., published a new method for heterogeneous particle motion tracking in the intracellular environment.
Quantification of Cell-to-Cell Morphological Heterogeneity
Bagonis et al. developed a robust, new method for the automated quantification of diverse, filopodia-rich, cellular morphologies such as neuronal growth cones.