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Cell mechanics orchestrates cell metabolism

Park et al. discovered a mechanism by which epithelial cells adjust glucose metabolism to extracellular matrix stiffness.

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How does cell shape shape cells?

Driscoll et al. publishes u-shape3D, a suite of computational tools to investigate how 3D cellular morphology governs intracellular signaling.

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Killer Lamellipodia

Mohan et al. publishes evidence for cell morphology dictating oncogenic proliferation signals.

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Coupling discrete and continuous signals

Azoitei, Noh et al. publish work that establishes based on a new biosensor and a novel statistical that microtubule catastrophe events promote activation of the RhoA GEF GEF-H1.

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A Sensitive Classifier for Endocytosis

Wang et al. developed an unsupervised classification for endocytosis based on a bimodality discovered in the disassembly dynamics of clathrin.

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