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Cell mechanics orchestrates cell metabolism
Park et al. discovered a mechanism by which epithelial cells adjust glucose metabolism to extracellular matrix stiffness.
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How does cell shape shape cells?
Driscoll et al. publishes u-shape3D, a suite of computational tools to investigate how 3D cellular morphology governs intracellular signaling.
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Killer Lamellipodia
Mohan et al. publishes evidence for cell morphology dictating oncogenic proliferation signals.
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Coupling discrete and continuous signals
Azoitei, Noh et al. publish work that establishes based on a new biosensor and a novel statistical that microtubule catastrophe events promote activation of the RhoA GEF GEF-H1.
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Quantification of Cell-to-Cell Morphological Heterogeneity
Bagonis et al. developed a robust, new method for the automated quantification of diverse, filopodia-rich, cellular morphologies such as neuronal growth cones.
