Research

Metabolic Hallmarks of Cancer

Metabolic reprogramming is now firmly established as a hallmark of cancer. Tumors share the common phenotype of uncontrolled cell proliferation which must be sustained by deviant metabolic processes. The required changes in metabolism are directly driven by successive oncogenic events and by the constraints imposed by the tumor microenvironment. Two areas of research in tumor metabolism that is investigated in the Corbin Lab include perturbations in cancer (I) Lipid Reprogramming and (II) Redox Biology.