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Kinase Regulation and Biology

We investigate how these kinases work in normal biology and are usurped in human disease.

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MAPK/ERK

The MAPK signaling network is a critical mediator of a host of cellular processes and a central pathway usurped in cancer.

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WNKs

Central regulators of ion homeostasis. Also essential in angiogenesis, cancer, and membrane trafficking.

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Nutrient Sensing

We explore the molecular mechanisms for recognition and responses to nutrients.