Publications for Elizabeth Chen, Ph.D.

Zhang, R.*, Lee, D.M.*, Jimah, J.R.*, Gerassimov, N., Yang, C., Kim, S., Luvsanjav, D., Winkelman, J., Metteln, M., Abrams, M.E., Kalia, R., Keene, P., Pandey, P., Ravaux, B., Kim, J.H., Ditlev, J.A., Zhang, G., Rosen, M.K., Frost, A., Alto, N.M., Gardel, M., Schmid, S.L., Svitkina, T.M., Hinshaw, J.E., and Chen, E.H. (2020) 
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
Nat. Cell Biol. 22, 674-688.

Kim, J.H. and Chen, E.H. (2019)
The fusogenic synapse at a glance 
J Cell Sci
. 132(18).

Lee, D.M. and Chen, E.H. (2019)
Drosophila Myoblast Fusion: Invasion and Resistance for the Ultimate Union
Annu. Rev. Genet. 53, 67-91.

Andrew, D.J., Chen, E.H., Manoli, D.S., Ryner, L.C., and Arbeitman, M.N. (2019)
Sex and the single fly: A perspective on the career of Bruce S. Baker 
Genetics 
212, 365-376.

Duan, R.*, Kim, J.H.*, Shilagardi, K.*, Schiffhauer, E., Lee, D.M., Son, S., Li, S., Thomas, C., Luo, T., Fletcher, D.A., Robinson, D.N., and Chen, E.H. (2018)
Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion
Nat. Cell Biol. 20, 688-698.

Shi, J.*, Bi, P.*, Pei, J., Li, H., Grishin, N.V., Bassel-Duby, R., Chen, E.H.#, and Olson, E.N.# (2017)
Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish
Proc. Natl. Acad. Sci. U.S.A 114, 11950-11955. 

Kim, J.H., Ren, Y, Ng, W.P., Li, S., Kee, Y.S., Son, S., Zhang, S., Zhang, G., Fletcher, D.A., Robinson, D.N., and Chen, E.H. (2015)
Mechanical tension drives cell membrane fusion
Dev. Cell 32, 561-573. 

Chen, E. and Sedwick, C. (2014)
Elizabeth Chen: Fusing cells press closer
J. Cell Biol. 206, 576-577.

Shilagardi, K., Li, S., Luo, F., Marikar, F., Duan, R., Jin, P., Kim, J., Murnen, K., and Chen, E.H. (2013)
Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion 
Science 340, 359-363.

Duan, R., Jin, P., Luo, F., Zhang, G., Anderson, N., Chen, E.H. (2012)
Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo 
J. Cell Biol. 199, 169-185.

Chen, E.H. (2011)
Invasive podosomes and myoblast fusion
In Membrane Fusion, L. V. hernomordik and M. M. Kozlov, eds. (Elsevier, USA), pp. 235-258. 

Jin, P., Duan, R., Luo, F., Zhang, G., Hong, N., and Chen, E.H. (2011)
Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo
Dev. Cell 20, 623-638.

Sens, K.L., Zhang, S., Jin, P., Duan, R., Zhang, G., Luo, F., Parachini, L., and Chen, E.H. (2010)
An invasive podosome-like structure promotes fusion pore formation during myoblast fusion
J. Cell Biol. 191, 1013-1027.

Zhang, S., and Chen, E.H. (2008)
Ultrastructural analysis of myoblast fusion in Drosophila
In Cell Fusion, E. H. Chen ed. (the Humana Press Inc., New Jersey), pp. 275-297.

Kim, S., Shilagardi, K., Zhang, S., Hong, S.N., Sens, K.L., Bo, J., Gonzalez, G.A., and Chen, E.H. (2007)
A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion 
Dev. Cell 12, 571-586.

Chen, E.H., Grote, E., Mohler, W.A., and Vignery, A. (2007)
Cell-cell fusion 
FEBS Letters 581, 2181-2193.

Chen, E.H., and Olson, E.N. (2005)
Unveiling the mechanisms of cell-cell fusion 
Science 308, 369-373. 

Chen, E.H., and Olson, E.N. (2004)
Towards a molecular pathway of myoblast fusion in Drosophila 
Trends in Cell Biology 14, 452-460.

Chen, E.H., Pryce, B.A., Tzeng J.A., Gonzalez, G.A., and Olson, E.N. (2003)
Control of myoblast fusion by a guanine nucleotide exchange factor, Loner, and its effector ARF6 
Cell 114, 751-762.

Chen, E.H., and Olson, E.N. (2001)
Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila
Dev. Cell 1, 705-715.