Publications for Elizabeth Chen, Ph.D.

Kim, J.H. and Chen, E.H. (2019)
The fusogenic synapse at a glance 
J Cell Sci
. 132(18). pii: jcs213124. doi: 10.1242/jcs.213124. Review.

Lee, D.M. and Chen, E.H. (2019)
Drosophila Myoblast Fusion: Invasion and Resistance for the Ultimate Union
Annu. Rev. Genet.
doi: 10.1146/annurev-genet-120116-024603. [Epub ahead of print]

Andrew, D.J., Chen, E.H., Manoli, D.S., Ryner, L.C., and Arbeitman, M.N. (2019)
Sex and the single fly: A perspective on the career of Bruce S. Baker 
212, 365-376.

Duan, R.*, Kim, J.H.*, Shilagardi, K.*, Schiffhauer, E., Lee, D.M., Son, S., Li, S., Thomas, C., Luo, T., Fletcher, D.A., Robinson, D.N., and Chen, E.H. (2018)
Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion
Nat. Cell Biol. 20, 688-698.*Co-first Author

Shi, J.*, Bi, P.*, Pei, J., Li, H., Grishin, N.V., Bassel-Duby, R., Chen, E.H.#, and Olson, E.N.# (2017)
Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish.
Proc. Natl. Acad. Sci. U.S.A 114, 11950-11955. *Co-first author, #Corresponding Author. 

Kim, J.H., Ren, Y, Ng, W.P., Li, S., Kee, Y.S., Son, S., Zhang, S., Zhang, G., Fletcher, D.A., Robinson, D.N., and Chen, E.H. (2015)
Mechanical tension drives cell membrane fusion.
Dev. Cell 32, 561-573. 

Chen, E. and Sedwick, C. (2014)
Elizabeth Chen: Fusing cells press closer.
J. Cell Biol. 206, 576-577.

Shilagardi, K., Li, S., Luo, F., Marikar, F., Duan, R., Jin, P., Kim, J., Murnen, K., and Chen, E.H. (2013)
Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion
Science 340, 359-363.

Duan, R., Jin, P., Luo, F., Zhang, G., Anderson, N., Chen, E.H. (2012)
Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo
J. Cell Biol. 199, 169-185.

Chen, E.H. (2011)
Invasive podosomes and myoblast fusion.
In Membrane Fusion, L. V. hernomordik and M. M. Kozlov, eds. (Elsevier, USA), pp. 235-258. 

Jin, P., Duan, R., Luo, F., Zhang, G., Hong, N., and Chen, E.H. (2011)
Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo
Dev. Cell 20, 623-638.

Sens, K.L., Zhang, S., Jin, P., Duan, R., Zhang, G., Luo, F., Parachini, L., and Chen, E.H. (2010)
An invasive podosome-like structure promotes fusion pore formation during myoblast fusion
J. Cell Biol. 191, 1013-1027.

Zhang, S., and Chen, E.H. (2008)
Ultrastructural analysis of myoblast fusion in Drosophila.
In Cell Fusion, E. H. Chen ed. (the Humana Press Inc., New Jersey), pp. 275-297.

Kim, S., Shilagardi, K., Zhang, S., Hong, S.N., Sens, K.L., Bo, J., Gonzalez, G.A., and Chen, E.H. (2007)
A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion
Dev. Cell 12, 571-586.

Chen, E.H., Grote, E., Mohler, W.A., and Vignery, A. (2007)
Cell-cell fusion
FEBS Letters 581, 2181-2193.

Chen, E.H., and Olson, E.N. (2005)
Unveiling the mechanisms of cell-cell fusion
Science 308, 369-373. 

Chen, E.H., and Olson, E.N. (2004)
Towards a molecular pathway of myoblast fusion in Drosophila
Trends in Cell Biology 14, 452-460.

Chen, E.H., Pryce, B.A., Tzeng J.A., Gonzalez, G.A., and Olson, E.N. (2003)
Control of myoblast fusion by a guanine nucleotide exchange factor, Loner, and its effector ARF6
Cell 114, 751-762.

Chen, E.H., and Olson, E.N. (2001)
Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila.
Dev. Cell 1, 705-715.