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Secreted Kinases

We study the phosphorylation of extracellular proteins by a novel family of secreted kinases.

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Secreted Phosphoproteins

We seek to understand the functional consequences of secreted protein phosphorylation. Many of these phosphoproteins are present in blood.

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Secreted Kinases and Human Disease

Secreted kinases play important roles in many biological processes, such as bone growth, wound healing, lipid homeostasis, and cancer.

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Methodology

We use biochemical and genetic approaches to study the role of secreted kinases in human health and disease.