The ubiquitin ligase parkin mediates resistance to intracellular pathogens.
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS Nature 2013 Sep 501 7468 512-6
cor, a Novel Carbon Monoxide Resistance Gene, Is Essential for Mycobacterium tuberculosis Pathogenesis.
Zacharia VM, Manzanillo PS, Nair VR, Marciano DK, Kinch LN, Grishin NV, Cox JS, Shiloh MU MBio 2013 4 6
Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages.
Manzanillo PS, Shiloh MU, Portnoy DA, Cox JS Cell Host Microbe 2012 May 11 5 469-80
Effect of carbon monoxide on Mycobacterium tuberculosis pathogenesis.
Zacharia VM, Shiloh MU Med Gas Res 2012 2 1 30
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection.
Shiloh MU, Manzanillo P, Cox JS Cell Host Microbe 2008 May 3 5 323-30
Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS Cell Host Microbe 2010 Mar 7 3 210-20
To catch a killer. What can mycobacterial models teach us about Mycobacterium tuberculosis pathogenesis?
Shiloh MU, DiGiuseppe Champion PA Curr. Opin. Microbiol. 2010 Feb 13 1 86-92
A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.
Hisert KB, MacCoss M, Shiloh MU, Darwin KH, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S, Holden DW, Murray D, Nathan C Mol. Microbiol. 2005 Jun 56 5 1234-45
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens.
Nathan C, Shiloh MU Proc. Natl. Acad. Sci. U.S.A. 2000 Aug 97 16 8841-8
Secretory leukocyte protease inhibitor, an inhibitor of neutrophil activation, is elevated in serum in human sepsis and experimental endotoxemia.
Grobmyer SR, Barie PS, Nathan CF, Fuortes M, Lin E, Lowry SF, Wright CD, Weyant MJ, Hydo L, Reeves F, Shiloh MU, Ding A Crit. Care Med. 2000 May 28 5 1276-82