Welcome

Recurrent MPGN in a renal allograft before (upper) and after (lower) treatment with plasmapheresis. Not resolution of subendothelial deposits.

Research Interests

Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; Molecular studies in lupus nephritis.

Publications

Saxena R, Frankel WL, Sedmak DD, Falkenhain ME, Cosio FG. Recurrent type I membranoproliferative glomerulonephritis in a renal allograft: successful treatment with plasmapheresis. Am J Kidney Dis. 2000 Apr;35(4):749-52.

Rovin BH, Lu L, Saxena R. A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochem Biophys Res Commun. 1999 Jun 7;259(2):344-8.

Ganz MB, Abu-Nader R, Saxena R, Grond J. Protein kinase C beta II isoform is up-regulated in human proliferative glomerulonephritis. Exp Nephrol. 1997 May-Jun;5(3):225-32.

Ganz MB, Saksa B, Saxena R, Hawkins K, Sedor JR. PDGF and IL-1 induce and activate specific protein kinase C isoforms in mesangial cells. Am J Physiol. 1996 Jul;271(1 Pt 2):F108-13.

Saxena R, Saksa BA, Hawkins KS, Ganz MB. Protein kinase C beta I and beta II are differentially expressed in the developing glomerulus. FASEB J. 1994 Jun;8(9):646-53.

Saxena R, Saksa BA, Fields AP, Ganz MB. Activation of Na/H exchanger in mesangial cells is associated with translocation of PKC isoforms. Am J Physiol. 1993 Jul;265(1 Pt 2):F53-60.