Publications

Recent Publications

Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Hypoxia Fate Mapping Identifies Cycling Cardiomyocytes in the Adult HeartNature. 2015 Jul 9;523(7559):226-30. Epub 2015 Jun 22. PMID: 26098368

Canseco DC, Kimura W, Garg S, Mukherjee S, Bhattacharya S, Abdisalaam S, Das S, Asaithamby A, Mammen PP, Sadek, HA. Human ventricular unloading induces cardiomyocyte proliferation. J Am Coll Cardiol. 2015 Mar 10;65(9):892-900. PMID: 25618530

Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response. Cell.  2014 Apr 24;157(3):565-79. PMID:24766806

Mahmoud AI, Kocabas F, Muralidhar S, Kimura W, Thet S, Porrello ER, Sadek HA. Meis1 Regulates Post-Natal Cardiomyocyte Cell Cycle Arrest. Nature. 2013 May 9;497(7448):249-53. Epub 2013 Apr 17. PMID: 23594737.

Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HARegulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92.

Kocabas F, Zheng J, Thet S, Copeland NG, Jenkins NA, Deberardinis RJ, Zhang C, Sadek HA. Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. Blood. 2012 Sep 20. PMID: 22995899.

Kocabas F, Mahmoud AI, Sosic D, Porrello ER, Chen R, Garcia JA, Deberardinis RJ, Sadek HA. The Hypoxic Epicardial and Subepicardial MicroenvironmentJ Cardiovasc Transl Res. 2012 May 8. PMID: 22566269.

Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. Transient regenerative potential of the neonatal mouse heart. Science. 2011 Feb 25;331(6020):1078-80. PMID: 21350179.

Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell. 2010 Sep 3;7(3):380-90. PMID: 20804973.