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The Psychoneuroendocrine Research Program (PNE) is under the direction of E. Sherwood Brown, M.D., Ph.D., Professor of Psychiatry at UT Southwestern Medical Center. We have been conducting research in mood, memory, and substance abuse since 1998.

Our current research focuses on two different areas: dual diagnoses (i.e., depression or bipolar disorders concurrent with medical illness or substance abuse) and the effects of corticosteroids (e.g., prednisone) on mood and memory.