Example of cortical actin density in transformed lung cancer cell model (left) and primary melanoma cell (right).
Causality in molecular pathways
We adopt mathematical methods from econometrics to infer causality between subcellular activities from live cell image data.
RHOA GEF role in mediating cell motility
Zaritsky, Tseng and colleagues have identified a surprising role for the Rho family GTPases in mediation of cell motility and cell-cell communication.
Tracking particle movement in dense environments
Roudot et. al., published a new method for heterogenous particle motion tracking in the intracellular environment.
New L1-norm regularization of traction force maps allow the resolution of force transduction in individual nascent adhesions.