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Causality in Molecular Pathways

We adopt mathematical methods from econometrics to infer causality between subcellular activities from live cell image data.

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Live Cell Imaging and Modeling

Example of vimentin and microtubule interaction measured in genome-edited epithelial cells during a wound healing response (left). Filament structure is extracted by network segmentation algorithm (middle) and interactions between cytoskeleton systems statistically analyzed (right). 

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CSPO Most Downloaded Paper

The Schafer et. al. article Differential KrasV12 protein levels control a switch regulating lung cancer cell morphology and motility was the new journal's most downloaded for 2015-2016. 

Meet the Lab

 

 

Software