Featured Clinical Research

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Healthy Volunteer Study

The Hypertension Section in the Division of Cardiology at the University of Texas Southwestern Medical Center at Dallas is conducting research to study effects of phosphate content in the diet and the nerve activity that controls blood pressure in healthy subjects, between the age group of 18-80 years with blood pressure between 120-129/80-84 mmHg.

Participants will receive health examination and blood tests at no charge. We are looking for healthy with no other medical problems such as diabetes mellitus, liver disease, or heart problems, who are not currently on treatment for high blood pressure.

If you are interested in this study, please contact our research personnel at (214) 648-3188 for further information.

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Blood Pressure Studies

The Hypertension Section in the Division of Cardiology at UTSW is conducting two blood pressure research studies:

Research to determine if lowering blood pressure with medication can reduce brain damage.

Participants will receive health examinations and blood tests at no charge. Blood pressure medications are provided at no cost to research participants. We are looking for participants with normal blood pressure and high blood pressure between the ages of 55-79 who have no history of stroke, dementia, heart or kidney disease, sleep apnea, autoimmune diseases, or carotid stents and stenosis. Time required for participation in this study is 6 weeks (normal blood pressure) to 1 year (high blood pressure). Research participants will be compensated. 

Research to compare the effects of 2 different types of potassium supplements on patients taking a diuretic for treatment of high blood pressure called Chlorthalidone.  

Participants will receive health examination and blood tests at no charge. The time required for participation in this study is 4-5 months. There will be compensation for each subject who participates in the study. We are looking for patients with treated or untreated blood pressure less than 160/100. We are seeking individuals who have no chronic medical problems such as diabetes, kidney disease, heart or liver disease, moderate or severe acid reflux disease, or chronic diarrhea. If you are taking BP medications, you will stop them and be put on chlorthalidone. You will have scheduled follow-up visits during the study.

If you are interested in either of these studies, please contact Danielle Pittman BSN, RN, CEN at 214-648-5940 for further information.

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Are you currently on medication for your depression but continue to have symptoms despite treatment?

The ASCERTAIN –TRD trial is currently recruiting patients to compare three types of treatments for patients with Treatment Resistant Depression (TRD) who are currently on an antidepressant.

Treatments will consist of:

  • Switching antidepressant medications;
  • Adding an additional antidepressant to their current medication;
  • Or adding Transcranial Magnetic Stimulation (TMS) while they continue their antidepressant medication.

All eligible participants will receive a treatment – there is no placebo in this trial. 

Participants must be between the ages of 18-80 and in a current episode of depression that has lasted for at least 12 weeks. 

To learn more or to see if you qualify, please contact us 214-648-HELP(4357) or cdrc@utsouthwestern.edu.

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Are you experiencing symptoms of menopause?

Feeling depressed or down? If you are a peri- or postmenopausal woman age 40-62 and:

  • Have experienced changes in your menstrual cycle in the past five years
  • Are experiencing significant menopause-related symptoms such as hot flashes
  • Are feeling down or depressed

You may be eligible for a research study at UT Southwestern evaluating a medication treatment for menopausal depression and other symptoms of menopause
Benefits include:

  • Study medication and monitoring of your menopausal symptoms at no cost
  • Compensation up to $520 for completing the 16-week study

Contact the PsychoNeuroEndocrine research group at 214-645-6953 or via Email

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Are you or a loved one suffering from Alzheimer’s disease?

This study is recruiting individuals ages 18 and up with Alzheimer’s disease who have symptoms of Agitation or Aggression.

Eligible participants will receive at no cost: medical evaluation, monitoring of memory and other intellectual functions, 12 weeks of study treatment with subsequent follow up.

A caregiver needs to be involved during the research study period

If interested, please call (214) 648-2806

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Vaginal Rejuvenation Study

The Plastic Surgery Department is conducting a study to evaluate the efficacy of IntraGen radiofrequency device and diVa hybrid fractional laser device in improving post-menopausal vulvovaginal symptoms.  Eligible subjects must be healthy, post-menopausal women between the ages of 40 and 65, presenting with one or more of the following symptoms: vulvar itching, burning, stinging, pain, irritation, dryness, discharge or odor.  Involvement in the study will consist of a screening visit, 3 treatment sessions, and 1 or 3 follow-up visits, depending on study arm.  Analysis will include, but is not limited to, questionnaire feedback, vaginal wall measurements, and micro-biopsy.  Participants will be compensated $25 per non-biopsy visit and $100 per biopsy visit.  To find out more information about this study or to get involved, PSresearch@mednet.swmed.edu the Department of Plastic Surgery Research. 

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