Breakthrough after breakthrough


Like the fictional Sherlock Holmes, UT Southwestern biochemist Dr. Zhijian “James” Chen approaches scientific mysteries by applying his keen observational skills and an uncanny ability to follow clues to their logical, satisfying conclusions.

Viral avenger


Dr. Julie Pfeiffer’s refusal to back down from a challenge pays off in her studies of poliovirus.

C(PRIT) into the future


Backed by a $6 million Cancer Prevention and Research Institute of Texas grant, UT Southwestern researchers are teaming up to study how radiation activates the immune system to fight cancer.

The maverick of big data


How did composing modern music and motivating teams under extreme environmental conditions contribute to Dr. Gaudenz Danuser’s unique perspective?

The frontier that lines the gut


Dr. Lora Hooper began the research for which she is now internationally known – studying the microbes that live inside the gut – just as the field took off.

Working smarter with AI


Imagine a future in which the clinic is wired with sensors that recognize you and streamline your visit.

A nano partnership with macro potential


An innovative digital pH sensor designed to improve the accuracy of tumor surgeries grew out of the unique, long-term collaboration of a cancer surgeon and a scientist.

Thirst for knowledge


Dr. David Mangelsdorf and Dr. Steven Kliewer first worked together as postdoctoral researchers. Parting ways, they became fierce but friendly competitors before joining forces again.

Teaming with insight


The unexpected partnership of Drs. Helen Hobbs and Jonathan Cohen laid the scientific foundation for a new class of cholesterol-lowering drugs and identified the first gene for the emerging threat of nonalcoholic fatty liver disease.

Looking forward: Better ways to take a closer look


From investing in the most advanced cryo-electron microscopy to building novel 3-D optical microscopes for cancer studies, UT Southwestern is at the forefront of using and creating the technologies needed to advance biomedical discovery.