The George M. O’Brien Kidney Research Core Center (NIH P30DK079328) was established at UT Southwestern Medical Center in 2007. Our goal is to support kidney research in kidney development and genetics, renal physiology, and chronic kidney disease that is conducted at UT Southwestern, neighboring institutions in North Texas, and the greater nephrology community in the U.S. and worldwide.

Dedicated to supporting research in kidney development and genetics, renal physiology, and chronic kidney disease.

The specific aims of our center are to generate new animal models to study the pathogenesis and treatment of human kidney diseases and their cardiovascular complications, accelerate the clinical application of discoveries made in renal basic science laboratories, and provide investigators with specialized tools and expertise to study kidney development, physiology, and pathophysiology.

To achieve these aims, the UT Southwestern O’Brien Kidney Research Center comprises four biomedical research cores: animal models, physiology, cell biology, pathology and imaging, and clinical and translational research. In addition, the Center offers an educational enrichment program consisting of biweekly seminars, an annual research conference, and hands-on training in research techniques. The pilot and feasibility program supports a project each year in the field of kidney research.