Awards for September 2017

Federal Awards

Banerjee, Subhash, UT Arlington/NIH, Novel Engineered Particle Platform for Endothelium Regeneration, $37,800; Beutler, Bruce (Fellow Z. Zhang), NIH, Role of KBTBD2 in Lipodystrophy, Insulin Resistance and Diabetes, $91,500; Blount, Paul, NIH, Using Small Compounds as Probes for Studying Mechanosensitive Channel Gating, $131,437; Butovich, Igor, NIH, Lipogenesis in the meibomian glands and adnexa in the norm and pathology, $405,000; Carroll, Thomas, Maine Medical Center Research Inst./NIH, Application of progenitor niche signals to ex vivo nephrogenesis, $396,777; Choi, Changho, NIH, Clinical development of cancer-specific MRS biomarkers in malignant gliomas, $329,925; Cleaver, Ondine, Maine Medical Center Research Inst./NIH, Application of progenitor niche signals to ex vivo nephrogenesis, $69,534; Davis, Laurie, U.S. Dept. of Defense, Next-Generation Biomarkers of Gulf War Illness, $453,440; De Gracia Lux, Caroline, U.S. Dept. of Defense, Eliminating ex-Vivo Manipulation and Viral Transfection of T-Cells in CAR-T Cell Immunotherapy of B-Cell Malignancies, $316,886; Deberardinis, Ralph, NIH, Metabolic Regulators of Tumor Growth and Progression, $961,705;

Elmquist, Joel (Fellow S. Wyler), NIH, Uncovering a mechanism for SF-1 transcriptional activation in response to exercise, $56,694; Floyd, Thomas, NIH, Spinal Fiber Optic Monitoring, $1,232,584; Galindo, Rene, NIH, Defective Myoblast Fusion Signaling in Rhabdomyosarcoma Pathogenesis, $370,575; Gao, Jinming, NIH, STING-Activating Polymeric Nanovaccines for T Cell Therapy of Melanoma, $535,530; Gardner, Lisa (Fellow A. Fernandez-Perez), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Gardner, Lisa (Fellow C. Bacon), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Gardner, Lisa (Fellow C. Gillis), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Gardner, Lisa (Fellow G. Hernandez), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Gardner, Lisa (Fellow I. Boys), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Gardner, Lisa (Fellow Z. Gallegos), Natl. Science Fdn., Graduate Research Fellowship, $46,000; Graff, Jonathan, NIH, Beige Adipocyte Development: lineage analysis and molecular characterization , $486,000; Gruchalla, Rebecca, Univ. of Wisconsin/NIH, Inner City Asthma Consortium 3 (ICAC3), $491,911;

Haley, Robert, UT Dallas/U.S. Dept. of Defense, Direct current stimulation for pain treatment of Gulf War Illness, $86,540; Halm, Ethan, Agency for Healthcare Research & Quality, UTSW Center for Patient-Centered Outcomes Research (PCOR), $1,000,001; Henkemeyer, Mark, Texas A&M Univ./NIH, Mechanism of ephrin signaling in mammalian palatal fusion, $28,162; Holland, William, NIH, Lipid Sensing in Pancreatic Alpha Cells, $405,000; Hon, Gary, NIH, Combinatorial Biology of Gene Regulation for Cellular Engineering, $165,101; Hsia, Connie, U.S. Dept. of Defense, Simultaneous Expression from Both the Sense an Antisense Strand of the Erythropoietin Receptor Gene Mitigates Acute Lung Injury, $107,238; Hsieh, Jer-Tsong, NIH, Developing targeted therapy with prostate cancer specific nanomedicine, $314,920; Hsieh, Jer-Tsong, UT Dallas/NIH, Surface Chemistry for High-contrast Fluorescent Kidney imaging, $19,002; Hulleman, John, NIH, Broadly applicable, regulatable strategy to control signaling in the retina, $243,000; James, Eric, NIH, Testing the dose-response of coordination training for older adults, $124,000;

Karp, David, Penn State Hershey Medical Center/NIH, Study of Anti-Malarials in Incomplete Lupus Erythematosus, $177,994; Lea, Jayanthi, Texas Tech Univ./U.S. Dept. of Defense, Novel platinum/taxane-based Drug Combinations (Preclinical) for Ovarian Cancer, $10,789; Li, Guo-Min, NIH, Deciphering the pathogenesis of pediatric high-grade gliomas, $72,163; Lin, Weichun, NIH, Patterning and Formation of the Neuromuscular Junction, $501,388; Liu, Zhi-Ping, U.S. Dept. of Defense, Epigenetic machinery regulates alternative splicing of androgen receptor (AR) gene in castration-resistant prostate cancer, $202,484; Lotan, Yair, Univ. of Hawaii/NIH, Multiplexed Protein Biomarker-Based Assay for the Detection of Bladder Cancer, $127,340; Maalouf, Naim, NIH, Optimizing Fluid Therapy and Stent Management in Children and Adults with Nephrolithiasis, $723,128; Madhuranthakam, Ananth, NIH, Quantitative Non-Contrast Perfusion using Arterial Spin Labeling for Assessment, $671,184; Mahendroo, Mala (Fellow S. Nallasamy), NIH, Mechanisms by which the myometrial ECM modulates myometrial cell function, $125,577;

Maldjian, Joseph, Wake Forest Univ./NIH, iTAKL: Imaging Telemetry & Kinematic-Modeling In Youth Football, $239,919; Malter, James, Univ. of Wisconsin/NIH, Role of Eosinophils in Airway Inflammation and Remodeling, $395,916; Mau, I-Fan, NIH, An Optimizer-Simulator for Phonosurgery, $388,120; Minna, John, NIH, Developing ASCL1 and NeuroD1 lineage oncogene targeted therapy for small-cell lung cancer, $605,070; Moore, William, UT Dallas/NIH, Dallas Lifespan Brain Study-Wave 3: Neurodegeneration & Resilience in Cognition, $29,197; North, Carol, Univ. of Southern Calif./NIH, Predictors of Major Depressive Disorder in Disaster Survivors, $7,674; Nwariaku, Ohwofiemu, NIH, Partnerships to Develop Injury Research Capacity in Sub-Saharan Africa, $221,233; Otwinowski, Zbyszek, Washington Univ. St. Louis/NIH, Structural Mechanisms of Ebola Virus RNA Synthesis, $42,499; Pan, Duojia, NIH, Control of Cell Number in Developing Retina, $405,000; Pedrosa, Ivan, Univ. of Wisconsin/NIH, Pedrosa Wisconsin Confounder-Corrected Quantitative MRI, $91,425;

Phillips, Margaret (Fellow W. Israelsen), NIH, Development and use of a novel, tractable rodent model for studies of hibernation, $392,600; Rogers, Zora, NIH, Baby Hug Follow-up Study II-Clinical Site, $156,698; Rutherford, Cynthia J, UT HSC Houston/HRSA, Great Plains Regional Hemophilia Network, $21,440; Scherer, Philipp (Fellow C. Crewe), NIH, Uncovering New Regulatory Mechanisms of Adiponectin Expression, $57,066; Scherer, Philipp (Fellow Y. Zhu), NIH, Gap Junction Dependent and Independent roles of Connexin43 in Metabolic Tissues, $91,500; Schneider, Frank, Saint Louis Univ./NIH, PTSD Treatment: Effects on Health Behavior, Cardiovascular and Metabolic Disease, $1,606; Self, David, NIH, Role of Extinction in Circuit-Specific Modulation of Motivation and Mood, $364,500; Skapek, Stephen, NIH, Physician Scientist Oncology Training Program, $290,866; Skapek, Stephen, Children’s Hosp. of Philadelphia/NIH, NIH NCTN Scientific Council, $15,000; Sun, Xiankai, UT Arlington/NIH, Radiotherapeutic Nanoseeds for Internal Radiation Therapy, $79,986;

Timmerman, Robert, Univ. of Maryland/NIH, Investigating Radiation-Induced Injury to Airways and Pulmonary Vasculature, $174,995; Vazquez, Miguel, NIH, Improving Chronic Disease Management with Pieces, $1,273,970; Vazquez, Miguel, NIH, Chronic Kidney Disease Precision Medicine Project, $340,000; Wakeland, Edward, U.S. Dept. of Defense, Objective Blood Test from Stimulated Gene Expression for Classification and Outcome Assessment in Clinical Trials of Gulf War Illness, $166,547; Wang, Tao, NIH, Development of integrative models for early liver toxicity assessment, $81,000; Wang, Yingfei, NIH, PARP-1 Signaling in DNA Damage and Cell Death, $405,000; Winick, Naomi, Children’s Hosp. of Philadelphia/NIH, NIH NCTN Scientific Leadership, $30,000; Wu, Jiang, NIH, Novel Non-Cell Autonomous Tumor Suppressor Function of H3K27me3 Demethylase UTX/Kdm6a in Medulloblastoma, $202,500; Yu, Gang, St. Jude Children’s Research Hosp./NIH, Multi-level Integrative Proteomics to Alzheimer’s Disease Pathways, $81,000;

Yu, Hongtao, NIH, Mitotic Checkpoint Regulators in Insulin Signaling, $299,700; Yu, Yonghao, NIH, Mass spectrometric approaches to protein ADP-ribosylation, $305,775; Zang, Qun, NIH, Pathological Responses to Mitochondrial ROS in Sepsis-Induced Cardiac Dysfunction, $291,600; Zhang, Rong (Fellow T. Tarumi), NIH, Midlife Brain Plasticity: Exercise and Vascular Function, $123,792.

Nonfederal Awards

Arteaga, Carlos, Breast Cancer Research Fdn., Oncogene signaling and therapeutic resistance to antiestrogens in breast cancer, $250,000; Bird, John, Food Allergy Research & Education (FARE), PITS: Peanut Sublingual Immunotherapy Induction of Clinical Tolerance, $47,997; Brion, Luc, Gerber Fdn., Individualizing and optimizing nutrition to prevent Metabolic Syndrome, $137,024; Chiang, Cheng-Ming, Welch Fdn., Mechanistic Action of BET Compound Inhibitors in Cancer Therapeutics, $65,000; Deberardinis, Ralph, CPRIT, Carbamoyl Phosphate Synthase-1: New metabolic liability in non-small cell lung cancers, $300,000; Dowling, Michael Morgan, UCSF/Pediatric Epilepsy Research Fdn., Seizures in Pediatric Stroke II (SIPS II), $11,150; Gardner, Lisa (Fellow N. Ramirez), Ford Fdn., Ford Foundation Fellowship, $24,000; Gupta, Rana, American Heart Assoc., Unlocking the Thermogenic Potential of White Adipose Tissue to Combat Obesity, $77,000; Hon, Gary, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $457,396;

Hooper, Lora (Fellow J. Brooks), Howard Hughes Medical Inst., Circadian Regulation of the Microbiota, $80,000; Hooper, Lora (Fellow S. Bel), EGL Charitable Fdn., Role of BCL2 in Regulating Antibacterial Autophagy in the Intestinal Epithelium, $76,520; Hooper, Lora (Fellow T. Harris-Tryon), Burroughs Wellcome Fund, Determining the function of resistin-like molecule a(RELMa) in cutaneous host defense, $140,000; Iyengar, Puneeth, American Cancer Society, Unchecked Adipocyte Lipolysis and Tumor Progression in Cachexia, $198,000; Jain, Raksha, Cystic Fibrosis Fdn., Effects of Estrogen on Inflammation and Infection in Cystic Fibrosis, $130,000; Konopka, Genevieve, Silicon Valley Community Fund, Single-cell RNA-seq analysis of human brain tissue, $152,734; Lin, Ken, Washington Univ. School of Medicine, Discovery and Functional Analysis of Proteins Regulated by Poly (ADP-Ribose) Polymerase-1 in Ovarian Cancer Cells, $108,000; Maldjian, Joseph (Fellow E. Davenport), Fdn. of the ASNR, MEG Spectral Analysis as a Biomarker in Alzheimer’s Disease, $99,952;

Malloy, Craig, CPRIT, TAMU-UT Southwestern Partnership for Breast Imaging and Spectroscopy at 7 Tesla, $299,415; McAdams, Carrie, Klarman Family Fdn., Biological Factors Related to Treatment-Refractory Anorexia Nervosa, $150,000; Munshi, Nikhil (Fellow S. Bhattacharyya), American Heart Assoc., Exploring Gata4 function during atrioventricular node formation, $26,844; O'Donnell-Mendell, Kathryn, LUNGevity Fdn., Dissecting novel mechanisms of lung cancer pathogenesis, $100,000; Okuda, Darin, UT Dallas/NIH, Effect of Neural-Vascular Coupling Changes on Cognitive Performance in Multiple Sclerosis, $46,254; Owen, David, Washington Univ. School of Medicine, Integrated Genomic Analysis of Placenta Development and Susceptibility to Zika Virus Infection Across Gestation, $135,000; Pan, Duojia (Fellow J. Phillips), Life Sciences Research Fdn., Utilizing unicellular organisms to characterize Hippo pathway regulation, $60,000; Pruitt, Sandi, Robert Wood Johnson Fdn., Multisector Solution to Build a Culture of Health Among Food Insecure Populations in Dallas County, $83,868; Reynolds, Kimberly, Gordon and Betty Moore Fdn., Decoding the Genome Using Evolutionary Statistics, $300,000;

Sadek, Hesham, CPRIT, Effect of Chest Radiation Therapy on Postnatal Cardiomyocyte Turnover, $299,262; Scherer, Philipp (Fellow N. Joffin), Lipedema Fdn., Phenotypic Analysis of Adipose Tissue from Lipedema Patients, $80,769; Tu, Benjamin, CPRIT, Targeting metabolic reprogramming event for early prevention of pancreatic cancers, $100,000.

Industry-Sponsored Awards, dollar amounts not available

Ahmed, Tasneem, Celgene, Phase 3 Study of Mongersen (GED-0301) for Active Crohn's Disease; Albuquerque, Kevin, Pfizer, Phase 2 trial of AntiPD-L1 and SAbR for Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer; Beg, Muhammad, Agios, Phase 3 Study of AG-120 for Cholangiocarcinoma with IDH1 Mutation; Carlson, Matthew, TESARO, Phase 1 Study of TSR-042 for Advanced Solid Tumors; Courtney, Kevin, Genentech, Phase 3 Trial of Ipatasertib for Metastatic Castrate-Resistant Prostate Cancer; Gerber, David, Criterium/Atomic, Phase 2 Trial of Brigatinib for Refractory ALK Rearranged NSCLC; Hussain, Mohammad, Novartis, Study of LCZ696 for Pediatric Patients with Heart Failure; Lee, William, Merck Sharp & Dohme, Phase 3 Study of MK-3682B for Chronic Hepatitis C; Murakami, Carol, Allergan, Aurora: Phase 3 Study of Cenicriviroc for Liver Fibrosis with Nonalcoholic Steatohepatitis;

Novakovic, Roberta, Mount Sinai School of Medicine, Wide-Neck Aneurysm Safety and Obliteration Study; Sathe, Meghana, Anthera, Phase 3 Study of Liprotamase for Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency; Szmuk, Peter, Masimo, Rainbow Acoustic Monitoring in Patients Weighing up to 10 kg; Tannin, Grace, Ascendis, Phase 3 Study of Transcon hGH for pre-pubertal children with Growth Hormone Deficiency.

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