Awards for November 2017

Federal Awards

Badawy, Mohamed, UC Davis/NIH, Validation of Decision Rules for CT Use in Children with Abdominal or Head Trauma, $64,773; Crandall, Craig, U.S. Department of Defense, Effects of burn injuries on thermoregulatory and cardiovascular responses in soldiers: Implications for the Standards of Medical Fitness, $394,178; Danuser, Gaudenz, Univ. of North Carolina at Chapel Hill/NIH, Spatio-temporal dynamics of GET- GT Pase networks, $278,250; Deberardinis, Ralph, NIH, Metabolic Characterization of Malignant and Non-Malignant Cells in Human Lung Tumors, $75,211; Gill, Michelle, Univ. of Wisconsin/NIH, Inner-City Asthma Consortium 3 (ICAC3), $293,362; Goldsmith, Elizabeth, Princeton Univ./NIH, Multiscale analysis of activating mutations in the RAS pathway, $31,250; Hsieh, Jenny, Stony Brook Univ./NIH, Circuitry mechanisms underlying new neuron development in adult and epileptic brain, $90,000; Hsieh, Jenny, Research Fdn. for Mental Hygiene/NIH, Diverse Roles of Adult Dentate Gyrus Neurogenesis, $60,671;

Hsieh, Jer-Tsong, U.S. Department of Defense, An association of unique microRNA turnover machinery with prostate cancer progression, $207,133; Hsieh, Jer-Tsong, U.S. Department of Defense, Epigenetic machinery regulates alternative splicing of androgen receptor (AR) gene in Castration-Resistant Prostate Cancer (CRPC), $204,120; Husain, Mustafa, Univ. of Toronto/NIH, Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression (CREST-MST), $230,324; Koh, Andrew, Giner/CDC, Highly Sensitive Electrochemical Assay to Monitor Gut Microbiome, $180,000; Kowalske, Karen, ACL-NIH-NIDILRR, North Texas Burn Rehabilitation Model System (NTBRMS), $380,000; Lega, Bradley, Columbia Univ./NIH, Role of Place and Grid Cells in Human Spatial Navigation and Memory, $45,059; Macdonald, Raymond, Univ. of Utah/NIH, Suppression of pancreatic tumorigenesis by the PTF1 transcription factor network, $22,451; Meeks, Julian, NIH, Investigating information processing in parallel circuits that link external chemical signals to social behavior, $218,200;

Minassian, Berge, Univ. of Kentucky Research Fdn./NIH, Genome editing, MRNA Suppression and Chain Termination as Therapy for Lafora Epilepsy, $293,094; Mitchell, Mack, Cleveland Clinic/NIH, Novel Therapies in Alcoholic Hepatitis, $243,543; Moe, Orson, NIH, UTSW O’Brien Kidney Research Core Center, $1,171,502; Rodriguez-Baez, Norberto, Johns Hopkins/NIH, Immunologic and Virologic Correlates of the Age-Related Decrease in HBV DNA in Children, $49,601; Rogers, Zora, The Medical Univ. of South Carolina/NIH, DISPLACE: Dissemination and Implementation of Stroke Prevention: Looking at the Care Environment, $29,999; Rosenbaum, Daniel, NIH, Structural elucidation and development of agonists for the human orexin receptors, $605,797; Rosenberg, Roger, Columbia Univ./NIH, Late Onset of Alzheimer’s Disease (LOAD) Family Based Study (FBS), $97,200; Rosenberg, Roger, Univ. of Washington/NIH, National Alzheimer’s Coordinating Center, $26,780;

Shay, Jerry, NIH, Cancer Biology Training Grant, $289,881; Skapek, Stephen, Indiana Univ./NIH, Developmental and Hyperactive Ras Tumor SPORE, $160,373; Skapek, Stephen, Children’s Hosp. of Philadelphia/NIH, COG Phase 1 Pilot Consortium, $8,741; Story, Michael, Galera Therapeutics/NIH, GC4419, an SOD Mimetic, as a Radiomodulator in Lung Cancer Patients, $101,969; Takahashi, Joseph, NIH, Cell-type-specific analysis of the suprachiasmatic nucleus, $354,375; Welch, Babu, Johns Hopkins/NIH, Advanced MRI methods to image vascular physiology with respiratory manipulations, $97,200; White, Perrin, NIH, Abiraterone Acetate in Children with Classic 21-Hydroxylase Deficiency, $656,253; Williamson, Jon, Dallas Fdn./U.S. Dept. of Health and Human Services, Project NTARUPT - Dallas Teenage Pregnancy Prevention Program, $75,944.

Nonfederal Awards

Abrams, John, CPRIT, Tumor suppression, p53 and retrotransposons, $272,057; Alluri, Prasanna, Asco Cancer Fdn., Targeting Estrogen Receptor Mutations for Treatment of Endocrine Therapy Resistance, $50,000; Alto, Neal, Burroughs Wellcome Fund, Seminar Award for Nels Elde, $1,000; Amatruda, James, Alex’s Lemonade Stand, DICER1-driven Cancers: Models, Mechanisms and Therapies, $125,000; Chen, Elizabeth (Fellow D. Lee), Canadian Institutes of Health Research, Investigating cell-cell fusion mechanism using optogenetics, $50,000; Cowell, Lindsay, Simon Fraser Univ., Immune receptor repertoire data commons for personalized immunotherapy, $125,000;

Danuser, Gaudenz (Fellow P. Roudot), Human Frontier Science Program, The cortex behind 3D migration: actin, myosin and adhesion dynamics, $55,620; D’Orso, Ivan, CPRIT, Probing Novel Concepts of the NF-kappaB Transcriptional Program in Human Cancer, $233,940; Haller, Ronald, Muscular Dystrophy Assoc., Impaired Oxidative Capacity in McArdle Disease: Causes and Treatment, $100,000; Hancks, Dustin, CPRIT, First-Time Tenure Track Faculty Member Award, $344,493; Kehoe, Siobhan, UT MD Anderson/CPRIT, Early Detection of Ovarian Cancer with Tumor Associated Proteins and Autoantibodies, $31,579; Kittler, Ralf, CPRIT, P3: Characterization of Cancer-Specific Gene Programs, $160,004; Li, Bing, Welch Fdn., Mechanisms of histone H3 lysine-to-methionine mediated chromatin misregulation, $65,000; Lin, Milo, Heising-Simons Fdn., Leveraging Symmetry to Predict Protein Self-Assembly, $70,380; Mahendroo, Mala, Washington Univ. in St. Louis/March of Dimes Fdn., Transdisciplinary Prematurity Research Center, $9,397; Nicastro, Daniela, CPRIT, Establish a new Cryo-Electron Microscopy Core Facility and service for structure determination, $2,141,302;

Pruitt, Sandi, Robert Wood Johnson Fdn., A Multisector Solution - Food Insecurity, $43,030; Rahn, David (Fellow J. Hamner), Medstar/SMSNA Fdn., STOMP: Sexual function Trial of Overactive bladder: Medication versus PTNS , $2,350; Sathe, Meghana, Cincinnati Children’s Hosp./Cystic Fibrosis Fdn., C3N Care Model of the Future: Proposal for Piloting a Learning Health System, $32,400; Singal, Amit, Baylor/CPRIT, Texas Hepatocellular Carcinoma Consortium (THCCC), $113,437; Sun, Xiankai, CPRIT, Cyclotron and Radiochemistry Core Facility for Pediatric Oncology, $1,453,096; Syeda, Ruhma, American Heart Assoc., Functional Characterization of mechanically activated channels, $77,000; Wang, Yingfei, CPRIT, Targeting a Novel Nuclease PAAN in Triple-Negative Breast Cancer, $100,000; Westover, Kenneth, CPRIT, HTS for covalent GTP-competitive inhibitors of KRAS G12C, $274,500; Zhang, Xuewu, CPRIT, Analyses of the regulatory mechanisms of tankyrase and its role in tumorigenesis, $299,997;

Industry-sponsored Awards, dollar amounts not available

Chin, Kelly, SoniVie Ltd., TROPHY1: Clinical study of the TIVUS System; Husain, Mustafa, Neosync Inc., Study of NEST sTMS for major depressive disorder; Khan, Saad, Bristol-Myers Squibb, Phase 2 Study of Nivolumab plus Ipilimumab for Carcinoma of the Head and Neck; Laetsch, Theodore, Children’s Oncology Group, Phase 1/2 Study of Lenvatinib plus Everolimus for Pediatric Solid Tumors; Mayo, Marlyn, Target Pharmasolutions, TARGET-PBC: 5-year Study of Patients with Primary Biliary Cholangitis; Miller, David, Advenchen Labs, Phase 1/2a Evaluation Adding AL3818 to Platinum-Based Chemotherapy; Miller, David, Xenetic Biosciences, Phase 2 Study of Sodium Cridanimod with Progestin Therapy for Endometrial Carcinoma;

Seikaly, Mouin, Relypsa Inc., Phase 2 Study of Patiromer Oral Suspension  for Pts < 18 Yrs with Chronic Kidney Disease and Hyperkalemia; Shen, Paul, Ra Pharma, Study of RA101495 for Paroxysmal Nocturnal Hemoglobinuria; Sher, David, Toshiba Corp., CIPHER: Phase 3 Trial of Carbon Ion Radiation Therapy for Pancreatic Cancer; Singal, Amit, AbbVie Inc., Study of HCV Antiviral Agents and Hepatocellular Carcinoma Recurrence in Patients with Cirrhosis; Zaha, Vlad, Boehringer Ingelheim, Phase 3 study of Empagliflozin for Chronic Heart Failure.

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