Federal Awards

Babb, Tony, NIH, Respiratory Effects of Obesity in Children, $570,602; Bobulescu, Ion, NIH, Role of Gut Bacteria and Renal Lipids in Obesity-related Kidney Disease, $364,500; Brown, Sherwood, NIH, Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators, $780,872; Brown, Sherwood, NIH, Dopamine-2 Receptor Partial Agonist for Bipolar Disorder and Alcohol Use Disorder, $563,831; Carroll, Thomas, NIH, UT Southwestern Summer Undergraduate Research Institute for the Study of Kidney Diseases, $100,764; Chalak, Lina, NIH, A Novel Wavelet Neurovascular Bundle for Real Time Detection of Injury in Neonatal Encephalopathy, $356,324; Chen, David, NIH, Pathway Choice of DNA Double-Strand Break Repair, $361,898;

Chopra, Rajiv, NIH, Image-Guided Doxorubicin Delivery for Pediatric Sarcomas, $579,143; Cruz, Ponciano, NIH, Dermatology Research Training Program, $129,259; Diamond, Marc, NIH, UT Southwestern Integrated Program for the Advancement of Neuroscience Research Careers, $81,309; Douglas, Peter, NIH, Cell Non-Autonomous Nature of the Heat Shock Response, $236,134; Elmquist, Joel, NIH, Interactions of Leptin and Central Serotonin Systems, $374,583; Elmquist, Joel, Baylor College of Med/NIH, PPARgamma in Vagal Sensory Neurons and the Untoward Effect of  Thiazolidinediones, $150,000; Elmquist, Joel (Fellow C. Castorena), NIH, Regulation of Energy Homeostasis via Cannabinoid 1 Receptors in the Ventral Media, $59,166;

Goldstein, Joseph (Fellow L. Engelking), NIH, SREBP-Mediated Lipid Regulation in the Intestine, $156,600; Hammers, Hans, Dept of Defense, Enhancing Immune Checkpoint Inhibitor Therapy in Kidney Cancer, $203,608; Hendrixson, David, NIH, Flagellar Motor Biogenesis in Polarly-Flagellated Bacterial Pathogens, $473,679; Herz, Joachim, NIH, Physiology and Pathophysiology of Apolipoprotein E Receptor-2 Splicing in Alzheimer's Disease, $405,000; Hu, Ming, NIH, Klotho: Therapeutic Agent for Ischemia Reperfusion Induced Acute Kidney Injury, $364,500;

Huber, Kimberly, NIH, Mechanisms of Neocortical and Sensory Hyperexcitability in Fragile X, $1,734,139; Huber, Kimberly, Emory Univ/NIH, FMRP Mechanism and Function, $57,232; Ivleva, Elena, NIH, Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia, $169,668; Jin, Eunsook, NIH, 13C Asymmetry in Blood Glucose as a Marker for Oxidative Stress in Liver, $69,165; Kohler, Jennifer, NIH, Photocrosslinking Probes to Discover Glycan-Dependent Interactions, $314,280; MacMillan, John, NIH, Center for High-Throughput Functional Annotation of Natural Products, $956,743; Makam, Anil, NIH, Role of Long-Term Acute Care Hospitals, $121,500; Mendelson, Carole, NIH, Mechanisms in the Regulation of SP-A Gene Expression, $115,411;

Mineo, Chieko, NIH, Endothelial Basis of Obesity-Induced Insulin Resistance, $405,000; Moe, Orson, NIH, Renal Control of Body Composition and Blood Pressure, $218,588; Monteggia, Lisa, NIH, MeCP2 Dependent Transcriptional Repression & Neurotransmission, $397,500; Morrison, Sean, NIH, The Regulation of Stem Cell Aging, $325,950; Munshi, Nikhil, NIH, Defining Regenerative Potential in the Cardiac Conduction System, $405,000; Olson, Eric, NIH, Myoediting of Duchenne Muscular Dystrophy, $1,569,794; Olson, Eric, NIH, Molecular Dissection of Myoblast Fusion in Muscle Development and Regeneration, $356,400;

Rahn, David, NIH, Investigation to Minimize Prolapse Recurrence of the Vagina using Estrogen (IMPROVE), $535,714; Rahn, David, NIH, Pelvic Floor Disorders Network, $266,085; Raskin, Philip, Tufts Med Ctr/NIH, Vitamin D and Type 2 Diabetes, $95,208; Roberts, Todd, NIH, Genes and Behavior: Reversible Knockdown of FoxP2 in Vocal Learning, $324,000; Sakhaee, Khashayar, NIH, Pathogenesis of Uric Acid Nephrolithiasis: The Multifaceted Role of Renal Lipids, $357,750;

Scherer, Philipp, NIH, Novel Mechanism Regulating the Adipocyte-Brain-Hepatocyte Axis, $1,958,638; Self, David, NIH, Basic Science Training Program in Drug Abuse Research, $531,031; Shiloh, Michael, NIH, Human Airway Microfold Cells in Mucosal Immunity to Bacterial Pathogens, $449,608; Singal, Amit, NIH, Harms of Hepatocellular Carcinoma Screening in Patients with Cirrhosis, $690,111; Sumer, Baran, NIH, pH Transistor Nanoprobes for Detection of Occult Nodal Metastases, $366,698; Trivedi, Madhukar, NIH, Translational Research Activities in Neuropsychiatry (TRAIN), $199,843; Wang, Zhigao, NIH, Molecular and Chemical Regulations of Necrotic Cell Death Pathways, $340,200; Wetzel, Dawn, Dartmouth College/NIH, The Role of Flagellar Motility to Innate Immune Recognition of Bacteria, $15,865;

Wise, Carol, NIH, Developmental Mechanisms of Human Idiopathic Scoliosis, $1,287,111; Word, Ruth, NIH, Elastic Fiber Homeostasis in the Vaginal Wall, $323,490; Word, Ruth, NIH, Genomic Consequences of Estrogen Receptor Activation in the Cervix, $243,000; Ye, Jin, NIH,  Proteolytic Activation of CREB3L1 in Treating Cancers and Tissue Fibrosis, $405,000; Zhang, Rong, NIH, Exercise and Intensive Vascular Risk Reduction in Preventing Dementia, $2,824,196; Zigman, Jeffrey, NIH, Mechanisms of Ghrelin Secretion, $364,500.

Nonfederal Awards

Alto, Neal, Welch Fdn, Post-Translational Modification of Host Enzymes by Bacterial Effector Proteins, $80,000; Amatruda, James, CPRIT, Targeting the HNF4A and WNT/Beta-Catenin Pathways in Childhood Malignant Yolk Sac Tumors, $285,069; Amatruda, James, Alex’s Lemonade Stand, Pediatric Oncology Student Training Program 2017, $5,000; Augustine, Martin (Fellow E. Dogeas), Soc for Surgery of Alimentary Tract, Dissecting the Mechanisms of Anti-EGFR Therapy Resistance in Colorectal Cancer through CRISPR/Cas9, $25,000; Barr, John (Fellow C. McDougall), Soc of Neurointerventional Surgery, Next Generation Brain Arteriovenous Malformation Model, $20,000; Bruick, Richard, Welch Fdn, Isoform-Selective Regulation of HIF-Alpha by Isoprenoids, $80,000; Chong, Benjamin, Rheumatology Res Fdn, Optimization of Clinical Trial Design in Cutaneous Lupus, $100,000;

Doncic, Andreas, CPRIT, Identifying Principles of Metabolic Signaling Pathway Integration Using Live Single-Cell Imaging, $326,210; D'Orso, Ivan, Welch Fdn, Cooperative Assembly of HIV Transcription Elongation Complexes, $65,000; Goldsmith, Elizabeth, American Heart Assoc, Reducing Stroke Severity through WNK3 Inhibition, $250,000; Grishin, Nick, Welch Fdn, Discovering New Chemistries with Whole Genome Sequencing, $80,000; Hannan, Raquibul, American Cancer Soc, Image-Guided Stereotactic Radiation Therapy of Primary Renal Cancer, $175,250; Henne, William, Searle Scholars Prgm, Novel Inter-Organelle Communication Networks in Lipid Metabolism and Neurological Disease and Aging, $100,000;

Herz, Joachim, BrightFocus Fdn, Targeting the Endosome for Alzheimer's Drug Discovery, $100,000; Hibbs, Ryan, McKnight Endowment Fund, Structure and Mechanism of Neuronal Acetylcholine Receptors, $75,000; Hibbs, Ryan, Welch Fdn, Structural Principles of Inhibitory Neurotransmitter Receptor Modulation, $65,000; Hon, Gary (Fellow S. Xie), American Heart Assoc, High-Throughput Analysis of Endogenous Enhancer Function, $50,350; Hulleman, John, Res to Prevent Blindness, Career Development Award, $75,000; Jain, Raksha, Cystic Fibrosis Fdn, Cystic Fibrosis Foundation – Adult Care Center, $171,010; Jaqaman, Khuloud, Welch Fdn, In Situ Measurement of Receptor Interaction Kinetics on the Cell Surface, $65,000;

Kerwin, Diana, Texas Health Resources/Rainwater Charitable Fdn, Tauopathy Research Projects, $109,632; Liu, Xin (Fellow L. Jiao), American Heart Assoc, Structural Mechanisms of Gene Silencing, $52,200; McFadden, David, St. Baldrick’s Fdn, Dissecting EWSR1-FLI1 Function in Ewing Sarcoma by Chemical Genetics, $110,000; Mendell, Joshua, CPRIT, DIS3L2 in Childhood Wilms Tumor: Mechanism to Medicines, $300,000; Michaely, Peter, American Heart Assoc, Differential Endosomal Sorting of LDLR by ARH and Dab2, $77,000; Morrison, Sean (Fellow E. Jeffery), Damon Runyon Cancer Res Fdn, Characterizing a New Hematopoietic Stem Cell Niche Factor, $56,000; Munshi, Nikhil, American Heart Assoc, Developing Biomarkers for Cardiac Dysrhythmias, $75,000;

Nijhawan, Deepak, Damon Runyon Cancer Res Fdn, Developing the Anti-Tumor Toxin CD437 into a New Cancer Therapy, $150,000; Nijhawan, Deepak, Welch Fdn, Expanding the Druggable Genome, $65,000; Olson, Eric (Fellow K. Baskin), American Heart Assoc, Med12 is Transcriptional Mediator of Cardiac Contractile Function, $54,150; Radhakrishnan, Arun, Welch Fdn, Molecular Mechanisms of Cholesterol Sensors in Human Cells, $65,000; Ranganathan, Rama, Welch Fdn, Principles of Allosteric Control in Proteins, $110,000; Ready, Joseph, American Chemical Soc, Enantioselective Atom Transfer Radical Additions to Olefins, $55,000;

Reese, Tiffany, American Heart Assoc, Inflammation, Gamma-Herpesvirus Reactivation and Lipid Homeostasis, $77,000; Seemann, Joachim, Welch Fdn, Biochemical and Structural Analysis of Golgi-based Spindle Assembly Activities, $65,000;

Shaul, Philip (Fellow L. Huang), American Heart Assoc, Endothelial Cell SR-BI and Atherosclerosis, $50,350; Shay, Jerry (Fellow J. Peters-Hall), Cystic Fibrosis Fdn, Telomerase Immortalized HBE Cells to Study Primary Defects of Mutant CFTR , $54,566; Skapek, Stephen (Fellow S. John), St. Baldrick’s Fdn, Targeting LILRB4 by CAR-T Cells for the Treatment of Pediatric AML, $91,909; Stowe, Ann (Fellow U. Selvaraj), American Heart Assoc, Stroke Induces Protective Neuronal Autoreactive Responses, $26,844; Tagliabracci, Vincent, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,001;

Terman, Jonathan, Welch Fdn, Chemistry and Enzymology of MICAL Family Oxidoreductases, $65,000; Wang, Sam, American College of Surgeons, Cell Type Specific Arid1a Loss Determines PDAC Precursor Identity, $40,000; Westover, Kenneth, Welch Fdn, Development of Covalent TAK1 Inhibitors, $65,000; Whitehurst, Angelique, St. Baldrick’s Fdn, Targeting Fragility in the TNFa Signaling Pathway in Ewing Sarcoma, $100,000; Zhu, Hao (Fellow A. Moore), Howard Hughes Med Inst, HHMI Fellowship, $38,000.

Industry Sponsored Awards, dollar amounts not available

Carr, Bruce, Abbvie, Phase 3 Extension Study of Elagolix for Premenopausal Heavy Menstrual Bleeding; Dowell, Jonathan, Precog, Phase 2 Study of Durvalumab for First Line Treatment of Unresectable Mesothelioma; Gerber, David, Viralytics, VLA-009 Phase 1 Study Of Cavatak for Late Stage Solid Tumors; Lee, William, Conatus Pharma, Trial of Emricasan for Decompensated Non-Alcoholic Steatohepatitis; Mammen, Pradeep, Phasebio Pharma, Assess Effects of Augmenting VIP Signaling in Murine Model of DMD Associated Cardiomyopathy; Posner, Bruce, Pfizer, Screen Pfizer Compounds to Determine Mechanism of Action of Families of Natural Products;

Ready, Joseph, Rodeo Therapeutics, Study of Small Molecule Inhibitors to Promote Tissue Repair and Regeneration; Shen, Yu-Min, RA Pharma, Phase 2 Study of RA101495 for Paroxysmal Nocturnal Hemoglobinuria; Singal, Amit, Target Pharmasolutions, 5-year Observational Study of Patients with Hepatocellular Carcinoma; Trivedi, Madhukar, Janssen Res & Dev, Study of Intranasal Esketamine for Major Depressive Disorder; Zhong, John, Cumberland Pharma, Study for Reduction in Fever and Pain in Pediatric Subjects Aged Birth to Six Months.

About UT Southwestern Medical Center

UT Southwestern, one of the premier academic medical centers in the nation, integrates pioneering biomedical research with exceptional clinical care and education. The institution’s faculty has received six Nobel Prizes, and includes 22 members of the National Academy of Sciences, 18 members of the National Academy of Medicine, and 14 Howard Hughes Medical Institute Investigators. The faculty of more than 2,700 is responsible for groundbreaking medical advances and is committed to translating science-driven research quickly to new clinical treatments. UT Southwestern physicians provide care in about 80 specialties to more than 100,000 hospitalized patients, 600,000 emergency room cases, and oversee approximately 2.2 million outpatient visits a year.

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