Awards for December 2017

Federal Awards

Amatruda, James Francis, Children’s Hospital of Philadelphia/NIH, NIH National Clinical Trials Network (NCTN) Grant - Project Every Child, $3,750; Bell, Kathleen Reilly, Baylor Scott & White Research Inst./ACL-NIH-NIDILRR, North Texas TBI Model Systems, $99,378; Brekken, Rolf Andrew, Houston Methodist Research Inst./NIH, Center for Immunotherapeutic Transport Oncophysics PSOC, $162,158; Buszczak, Michael, NIH, Regulation of mRNA translation during germline cyst differentiation, $324,000; Carroll, Thomas, Maine Medical Center Research Inst./NIH, Application of Progenitor Niche Signals to Ex Vivo Nephrogenesis, $162,117; Chen, David, UC Berkeley/NIH, Progress Report Year 2-SPA1377: Structural Cell Biology of DNA Repair Machines, $56,700; Chong, Pearlie Pao Ee, Northwestenr Univ./NIH, Multi‐Center, Prospective, Randomized, Double‐Blind Study of Nitazoxanide in Acute and Chronic Norovirus , $71,200; Cleaver, Ondine, NIH, GTPases as molecular gatekeepers of cytoskeletal and cellular polarization, $376,717.

Elmquist, Joel K (Fellow - C. Castorena), NIH, Endocannabinoids: Obesity and Insulin Resistance, $121,164; Gimpel, Nora Esther, Texas A&M Research Fdn./Health Resources and Services Admin., Predoc training in General Pediatric & Public Health Dentistry-Year 3, $26,629; Gimpel, Nora Esther, Texas A&M Univ. System/Health Resources and Services Admin., Dental Faculty Development and Loan Repayment Program, $14,112; Herz, Joachim, NIH, Molecular Basis of Synaptic Suppression by ApoE, $364,500; Hsia, Connie C, NIH, Structural Plasticity in Compensatory Lung Growth and Remodeling, $676,403; Huen, Sarah, NIH, The Role of Kidney FGF21 in Surviving Sepsis , $169,560; Kerwin, Diana Rose, UC San Francisco/NIH, The Frontotemporal Lobar Degeneration Clinical Research Consortium, $31,757; Konopka, Genevieve, NIH, Functional dissection of mammalian vocal communication, $309,825; Kramer, Helmut, NIH, Genetics of Endocytic Trafficking in the Drosophila Eye, $364,500.

Laetsch, Theodore, Univ. of Colorado, Denver/NIH, Study of Eribulin in Combination with Oral Ironotecan for Adolescent and Young Adult Patients YR2, $14,999; Le, Lu Quang, Indiana Univ./NIH, Developmental and HyperActive Ras Tumor SPORE, $92,484; Le, Lu Quang, U.S. Army Medical Research, Parallels between Nerve Scar Formation and Neurofibroma Development, $81,000; Li, Guo-Min, NIH, Novel Mechanism Ensuring Replication Fidelity, $287,955; Liou, Jen, NIH, Functions and regulation of endoplasmic reticulum-plasma membrane junctions, $284,904; Luo, Xuelian, Massachusetts General Hosp./NIH, Chemical approach to study autopalmitoylation of transcription factors, $104,736; Mason, Ralph Peter, NuvOx Pharma/NIH, Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation , $30,419.

McClintock, Shawn, Univ. of New Mexico Medical Center/NIH, ECT Pulse Amplitude and Medial Temporal Lobe Engagement, $7,431; Morrison, Sean Joseph (Fellow - A. DeVilbiss), NIH, Role of HSF1 in Hematopoietic Stem Cell Maintenance and Function, $57,066; Mukhopadhyay, Saikat, NIH, Signaling at the primary cilium in development and disease, $249,318; Nakonezny, Paul, Mayo Clinic Rochester/NIH, Glutamatergic and GABAergic Biomarkers in rTMS for Adolescent Depression, $17,559; Nijhawan, Ank, NIH, Reducing Readmissions and Improving Outcomes in HIV-Infected Patients, $178,169; Olson, Eric, NIH, Deciphering the role of a novel micropeptide in cardiac function and dysfunction, $555,460; Otwinowski, Zbyszek, Northwestern Univ./U.S. Dept. of Health and Human Services, Center for Structural Genomics for Infectious Diseases , $39,580; Perez-Fontan, Julio, NIH, Antecedants  Sequelae of Childhood Onset Disease, $357,642; Phillips, Margaret Anna (Fellow - L. Buhrow), NIH, Targeting lipid metabolism for the treatment of malaria, $63,078; Raskin, Philip, George Washington Univ./NIH, Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE), $120,615; Roberts, Todd Freeman, National Science Fdn., NSF-17-1  EAGER: Novel Viral Vectors for Neuroscience Research, $149,999; Rohatgi, Anand Kumar, NIH, The Genetic and Molecular Basis of Cholesterol Efflux, $831,391; Rosenbaum, Daniel Mark, NIH, Molecular mechanism of a master regulator of sterol homeostasis, $277,829; Roth, Michael Gordon, NIH, HTS for discovery of inhibitors of the centrosome-independent mitotic spindle machinery, $370,575.

Shaul, Philip Warren, NIH, Dichotomous Role of Endothelial SR-BI in Atherosclerosis, $396,900; Sherry, Dean, NIH, Paracest Agents for Molecular Imaging of Cancer by MRI, $277,020; Singal, Amit, U.S. Dept. of Defense, Defining hepatocellular carcinoma subtypes and treatment responses in patient derived tumorgrafts, $93,092; Sperandio, Vanessa, NIH, Quorum Sensing Regulation of EHEC Virulence Genes, $567,000; Van Oers, Nicolai, NIH, Long noncoding RNAs and their contribution to 22q11 deletion syndrome, $432,410; Westover, Kenneth Dale, U.S. Department of Defense, Fragment-Based Approaches to Enhance GTP Competitive KRAS G12C Inhibitors, $283,500; Winick, Naomi Joan, Children’s National Medical Center/NIH, Longitudinal, multimodal assessment of neuropsychological functioning, $18,881; Word, Ruth Ann, Genome Design Lab/NIH, Rat Germline Gene Editing Products and Services, $28,941.

Nonfederal Awards

Amatruda, James Francis, Dana-Farber Cancer Inst./St. Baldrick’s Fdn., Malignant Germ Cell Tumors International Consortium, $179,009; Arteaga, Carlos Luis, Susan G. Komen Breast Cancer Fdn., MCL1 and chemotherapy resistance in triple negative breast cancer, $60,000; Augustine, Martin Mathew (Fellow - E. Dogeas), Alpha Omega Alpha Honor Medical Society, Dissecting the Mechanisms of Anti-EGFR Therapy Resistance in Colorectal Cancer through CRISPR/Cas9 Loss- and Gain-of-function, $2,000; Brown, Edson Sherwood (Fellow - B. Cenik), NARSAD, Novel Sterol Biomarkers in Depression, $34,994; Butts, Ryan, Hospital for Sick Children, Development of a Risk Calculator to Predict Sudden Cardiac Death in Children with Hypertrophic Cardiomyopathy, $1,176; Carlson, Matthew, Women & Infants Hosp./Patient-Centered Outcomes Research Inst., Cancer of the Uterus and Treatment of Urinary Incontinence, $12,602; Chen, Elizabeth, American Heart Assoc., A role of invasive podosomes in vertebrate myoblast fusion, $80,000.

Cobb, Melanie Houston, American Cancer Society, Institutional Research Grant, $120,000; Cullum, C Munro, Texas Council on Alzheimer’s Disease and Related Disorders, Genetic and Biomarker Study of Alzheimer’s Disease, $150,000; Gibson, Jay R, Simons Fdn., Foxp1 orchestration of neuronal function in the striatum, $148,850; Hannan, Raquibul, UT Dallas/CPRIT, Radiation-induced release of chemotherapeutic agents in vivo, $50,000; Huber, Kimberly, Simons Fdn., Defining the Translational Landscape in Mouse Models of Autism, $137,500; Jain, Mamta, Gilead Sciences, Eliminate HCV Through Expansion of HCV Treatment, Education, Care Coordination, and Patient Navigation to Re-engage HIV/HCV P, $197,925; Jain, Raksha, Cystic Fibrosis Fdn., Proposal for additional PI protected effort, $24,460; Jain, Raksha, Cystic Fibrosis Fdn., Adult Therapeutics Development Network Additional Research Coordinator Award, $19,211; Jiang, Steve Bin, CPRIT, Towards Carbon Beam Stereotactic Body Radiation Therapy (C-SBRT) , $819,690; Kennard, Beth, Texas Health Resources, Neural Control and Cardiac-Vascular Function in Women with PTSD, $8,000; Kim, Daehwan, CPRIT, Daehwan Kim CPRIT Recruitment, $531,527; Luo, Weibo, CPRIT, The Role of Hypoxia-Inducible Factor 1 in Breast Cancer, $500,000; Luo, Weibo, Susan G. Komen Breast Cancer Fdn., Epigenetic regulation of hypoxia-inducible factor 1 activity in breast cancer, $150,000.

Morrison, Sean Joseph, CPRIT, The role of the CACNA1D calcium channel in melanoma, $99,912; Olson, Daiwai, Sigma Theta Tau International, Sound in Neuroscience Intensive Care Unit (SoNIC), $1,000; Olson, Eric (Fellow - L. Amoasii), American Diabetes Assoc., A Molecular Mechanism that Mimics Exercise and Resists Metabolic Syndrome, $59,128; Plattner, Florian, NARSAD, The role of cAMP/PKA Signaling mechanisms in major depressive disorder, $35,000; Ross, Theodora Suzanne, CPRIT, Detecting Unaffected Individuals for Lynch Syndrome (DUAL): Screening, Diagnosis , $694,092; Ross, Theodora Suzanne, CPRIT, Use of Genetic Patient Navigators to Help Mutation Carriers Comply with the NCCN , $132,013; Sadek, Hesham, Fondation Leducq, Redox Regulation of Cardiomyocyte Renewal, $178,200; Winick, Naomi Joan, St. Baldrick’s Fdn., Feasibility of Home-Based Computerized Training During Maintenance Therapy, $47,742; Yu, Hongtao, UT MD Anderson Cancer Center/CPRIT, DNA-Protein Crosslink Repair Pathways and Cancer Therapy, $152,197.

Industry-sponsored Awards, dollar amounts not available

Bird, John, Aimmune Therapeutics, Long-term study of AR101 Characterized Oral Desensitization Immunotherapy; Byarlay,Mark, Theravance Biopharma, Phase 2 Study of TD-9855 for Neurogenic Orthostatic Hypotension; Chin, Kelly, Actelion Pharma, Study of intravenous selexipag for stable pulmonary arterial hypertension; Friedman,Deborah, Axon Optics, Spectacle Tints and Thin-Films to Reduce Headache Frequency in Chronic Migraine; Gordon, Erin, Prolacta Bioscience, Study of infants with single ventricular physiology fed an exclusive human milk diet following surgical repair; Husain, Mustafa, Avanir Pharma, Phase 3 Study of AVP-786 for Treatment of Agitation in Alzheimer’s Dementia; Khan, Saad, AbbVie Inc., Phase 3 Study of Rovalpituzumab Tesirine for DLL3 Small Cell Lung Cancer; Khan, Saad, Yale Univ., Phase 2 Study of Pembrolizumab for head and neck squamous cell carcinoma; La Hoz, Ricardo, Scynexis Inc., Study of SCY-078 for Fungal Infections that are Intolerant of Standard Antifungal Treatment; Lingvay, Ildiko, Novo Nordisk, Study of subcutaneous semaglutide for non-alcoholic steatohepatitis; Mayo, Marlyn, GENFIT, Phase 2 Study of Elafibranor for Primary Biliary Cholangitis; Naqvi, Syed, Cincinnati Children’s Hosp., Study of Early Onset Childhood Narcolepsy: Recent Cases and Post Infection Human Subjects; Oz, Orhan, Cyclomedica Australia, Comparison of Technegas and Xenon 133 Planar Lung Imaging for Ventilation Scintigraphy; Sue, Paul, Astellas Pharma Global Development, Phase 1 Study of Intravenous Isavuconazonium Sulfate in Pediatric Patients.

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