Federal Awards

Beutler, Bruce, Scripps Res Inst/NIH, U19 Project 1 Systems Approach, $853,723; Beutler, Bruce, Scripps Res Inst/NIH, U19 Core A Systems Approach, $808,821; Beutler, Bruce, Scripps Res Inst/NIH, U19 Core C Systems Approach, $313,969; Blount, Paul, NIH, Molecular Mechanisms of Mechanosensitive Channel Gating, $113,050; Brown, Sherwood, NIH, Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators, $825,118; Burgess, Shawn (Fellow D. Cappel), NIH, Anaplerotic and Oxidative, $52,406; Chen, David, Univ of Cal, Berkeley/NIH, Structural Cell Biology of DNA Repair Machines, $75,108; Crandall, Craig, Dept of Defense, Effects of Burn Injuries on Thermoregulatory and Cardiovascular Responses in Soldiers: Implications for Standards of Medical Fitness, $430,892;

Danuser, Gaudenz, Northwestern Univ/NIH, Regulation and Function of Intermediate Filaments in Cell Mechanics- Project 3, $289,336; Douglas, Peter, NIH, Cell Non-Autonomous Nature of the Heat Shock Response, $248,999; Elmquist, Joel, NIH, Interactions of Leptin and Central Serotonin Systems, $373,427; Gerber, David, Dept of Defense, Phase 0 Trial of Itraconazole for Early-Stage Non-Small Cell Lung Cancer, $225,528; German, Dwight, NIH, Diagnostic and Prognostic Biomarkers for Parkinson's Disease, $515,427; Gill, Michelle, Univ of Wisconsin/NIH, Mechanistic Study Development for ICAC3 MUPPITS and CoNAC Protocols, $78,203; Goldsmith, Elizabeth, Princeton Univ/NIH, Multiscale Analysis of Activating Mutations in the RAS Pathway, $229,033; Grishin, Nick, NIH, Computational Methods for Structural-Functional Studies of Protein, $287,975;

Haley, Robert, Dept of Defense, GWI Blood Test – An Objective Blood Test from Stimulated Gene Expression for Classification and Outcome Assessment in Clinical Trials of Gulf War Illness, $511,589; Halm, Ethan, Agency for Healthcare Res & Qual, UT Southwestern Center of Patient-Centered Outcomes Research (PCOR), $999,998; Holland, William, NIH, Adiponectin Receptors and S1P Signaling in Beta Cell – Supplement, $161,500; Hsieh, Jenny, Dept of Defense, Optogenetic Intervention of Post-Traumatic Epilepsy, $184,816; Hsieh, Jer-Tsong, UT Dallas/NIH, Surface Chemistry for High-Contrast Fluorescent Kidney Imaging, $18,611; Hu, Ming, NIH, Klotho: Therapeutic Agent for Ischemia Reperfusion Induced Acute Kidney Injury, $345,825; Hu, Ming, NIH, Klotho: Therapeutic Agent for Ischemia Reperfusion Induced Acute Kidney – Supplement, $121,125; Idris, Ahamed, Univ of Alabama/NIH, Pragmatic Airway Resuscitation Trial (PART), $24,192;

Jimenez, Patricia, Washington Univ in St. Louis/NIH, Hormonal Regulation of miRNAs Critical to Implantation and Decidualization, $128,600; Johnson, Mark, Univ of Miami/NIH, Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease (MyRIAD), $18,042; Kim, James, Dept of Defense, Targeting of Cancer Stem Cells and Their Microenvironment in Early Stage Mutant K-ras Lung Cancer, $190,794; Konopka, Genevieve, Georgia Inst of Tech/NIH, Human Specific Brain DNA Methylation and Neuropsychiatric Diseases, $149,605; Kozlitina, Julia, NIH, Genetic Factors in Taste Perception and Tobacco Usage, $430,518; Lee, William, NIH, Multi-Center Group to Study Acute Liver Failure, $3,475,240; Levine, Benjamin, NASA, Integrated Cardiovascular (ICV) 2.0, $100,000; McKnight, Steven (Fellow W. Israelsen), NIH, Development and Use of a Novel, Tractable Rodent Model for Studies of Hibernation, $373,000; Miller, David, NRG Oncology/NIH, NRG Oncology Network Group Operations Center, $15,000;

Mirpuri Hathiramani, Julie, NIH, Impact of Maternal High Fat Diet on the Gut Microbiota and Th17 Axis in Offspring, $152,014; Mitchell, Mack, Cleveland Clinic Fdn/NIH, Novel Therapies in Alcoholic Hepatitis, $282,673; Moe, Orson, NIH, Renal Control of Body Composition and Blood Pressure, $62,199; Neeland, Ian, NIH, Visceral Adiposity and Diabetes: Translating Form to Function Using Imaging, $153,360; Nijhawan, Ank, Miriam Hosp/NIH, Improving Linkage to Care Following Release from Incarceration, $34,795; Olson, Eric, NIH, Myoediting of Duchenne Muscular Dystrophy, $1,564,956;

Otwinowski, Zbyszek, NIH, X-ray Data Analysis in the Presence of Structural Variability, $350,040; Otwinowski, Zbyszek, Northwestern Univ/NIH, Center for Structural Genomics of Infectious Diseases, $162,164; Rahn, David, NIH, Investigation to Minimize Prolapse Recurrence of the Vagina using Estrogen (IMPROVE), $1,545; Raj, Ganesh (Fellow L. Miao), Dept of Defense, Disruption of the Interaction of the Androgen Receptor with Chromatin, $62,057; Raskin, Philip, Tufts Univ/NIH, Vitamin D and Type 2 Diabetes (D2d Study), $47,612; Sakhaee, Khashayar, National Marine Mammal Fdn/Office of Naval Res, Prevention and Treatment Strategies for NH4U Nephrolithiasis in Navy Dolphins, $63,912; Scherer, Philipp, NIH, Adiponectin, A Protein Secreted from Adipose Tissue, $446,992; Scherer, Philipp (Fellow Q. Wang), NIH, Converting more Brown Adipocytes from Resting to Active State, $111,963;

Schmid, Sandra, NIH, Defining the Role of Dynamin in Endocytosis – Admin Supplement, $112,759; Schneider, Jay, Univ of Maryland/NIH, Progenitor Cell Biology Consortium Administrative Coordinating Center, $17,123; Self, David, McLean Hosp/NIH, Role and Regulation of Class IIA HDACs in Cocaine Addiction, $9,074; Shaul, Philip, Univ of Cincinnati/NIH, Role of Endothelial and Macrophage ApoER2 in Atherosclerosis Modulation, $341,798; Sherry, Dean, NIH, Imaging Beta Cell Function in Vivo with Zinc Responsive MRI Contrast Agent, $345,825; Souza, Rhonda, NIH, Reflux-Induced Epithelial-Mesenchymal Transition in Benign Barrett’s Esophagus, $283,500;

Tagliabracci, Vincent, NIH, Phosporylations of FGF23 Coordinates Crosstalk Between the Skeleton and Kidney, $248,410; Tamminga, Carol, NIH, Psychosis and Affective Research Domains and Intermediate Phenotypes (PARDIP), $237,881; Thibodeau, Jennifer, Univ of Michigan/NIH, Revival Registry Evaluation of Vital Information for VADs in Ambulatory Life, $91,527; Trivedi, Madhukar, NIH, Clinical Trials Network: The Texas Node – Supplement CTN-0064, $342,989; Trivedi, Madhukar, NIH, Clinical Trials Network: The Texas Node – Supplement CTN-0037 and CTN-0053, $126,367; Wakeland, Edward, Dept of Defense, GWI Blood Test – An Objective Blood Test from Stimulated Gene Expression for Classification and Outcome Assessment in Clinical Trials of Gulf War Illness, $202,964;

Wan, Yihong, Dept of Defense, MicroRNA as Novel Suppressor of Osteoclastogenesis and Bone Metastasis of Breast Cancer, $198,750; White, Perrin, NIH, Abiraterone Acetate in Children with Classic 21-Hydroxylase Deficiency, $680,615; Word, Ruth, NIH, Cervical Ripening and Histone Acetylation, $242,250; Wyckoff, Myra, RTI Intl/NIH, NICHD Neonatal Research Network Capitation Funding, $37,050; Yu, Yonghao, NIH, Molecular and Biochemical Basis of mTORC1-mediated Feedback Loops, $318,963; Zhong, Qing, NIH, Biochemical Dissection and Reconstitution of Autophagic Membrane Fusion, $318,963.

Nonfederal Awards

Ahn, Chul, CPRIT, C1: Biostatistical Core, $54,389; Amatruda, James, CPRIT, P3: Functional Validation of Actionable Mutations in Sarcoma Genetic Model Systems, $355,486; Amatruda, James, CPRIT, C1: Central Sarcoma Processing Core, $166,471; Amatruda, James (Fellow K. Chen), Damon Runyon Res Fdn, Dysregulation of the N-myc/Lin28/let-7 Axis in Childhood Wilms Tumors, $62,000; Argenbright, Keith, CPRIT, Population Based Screening for Hereditary Breast and Ovarian Cancer, $490,706; Banaszynski, Laura, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $487,797; Bibb, James (Fellow A. Carter), American Cancer Soc, Identification of Therapeutic Targets for Neuroendocrine Cancer, $52,000; Brekken, Rolf, CPRIT, P4: Radiation-Guided Vascular Targeting of Lung Cancer, $278,128;

Chen, Zhijian, CPRIT, P3: Mechanisms Underlying Inflammation and Cell Death in Cancer, $320,341; Chen, Zhijian, CPRIT, C2: Proteomics Core, $233,884; Chiang, Cheng-Ming, CPRIT, Targeting BRD4 in Breast Cancer, $300,000; Cobb, Melanie, CPRIT, Dependence of Small Cell Lung Cancer on the Basic Helix-Loop-Helix Transcription, $300,000; De Brabander, Jef, CPRIT, C1: Chemistry and Pharmacology Core, $209,970; Durakoglugil, Murat, Darrell K Royal Fund for Alzheimer’s Res, NMDA Receptor Regulation in Alzheimer's Disease and Memory Enhancement, $55,000; Engelking, Luke, Gilead Sciences Inc, Gilead Research Scholar Award, $65,000;

Fontoura, Beatriz, CPRIT, P2: Intersections between Viral-Host Interactions and Oncogenic Pathways as Molecular Targets for Chemical Intervention, $315,789; Gao, Jinming, CPRIT, Turn ON the Tumor Contrast for Surgical Resection of Head and Neck Cancers, $300,000; Gardner, Lisa (Fellow A. Nevarez), Ford Fdn Fellowship Prgm, Ford Foundation – Nevarez, A., $24,000; Gardner, Lisa (Fellow M. Driscoll), Howard Hughes Med Inst, HHMI – Fung, HYJ, $43,000; Greenberg, Benjamin, Patient-Ctred Outcomes Res Inst, Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate (CAPTURE) Study, $362,122; Haller, Ronald, Muscular Dystrophy Assoc, Impaired Oxidative Capacity in McArdle Disease: Causes and Treatment, $100,000;

Hsieh, Jer-Tsong, CPRIT, C1: Translational Core, $211,831; Hsieh, Jer-Tsong, UT Dallas/CPRIT, Mapping Acidic Tumor Microenvironment with Renal Clearable pH Nanoindicators, $109,219; Iannaccone, Susan, Nationwide Children’s Hosp/Muscular Dystrophy Assoc, MDA Duchenne Muscular Dystrophy Clinical Research Network, $60,000; Kittler, Ralf, CPRIT, P3: Characterization of Cancer-Specific Gene Programs Regulated by Nuclear Receptors and Co-Regulators, $160,004; Levine, Benjamin, Partnership for Clean Competition, Safety, Efficacy and Detection of Xenon Supplementation for Increased Red Cell Mass in Highly Trained Athletes, $215,335; Levine, Beth, CPRIT, P1: Selective Autophagy Molecules as Multifunctional Regulators of Innate Immunity and Oncogenesis, $315,244; Liu, Xin, Rita Allen Fdn, Structural and Mechanistic Studies of Promoter-Terminator Gene Looping, $100,000;

Liu, Zhi-Ping, CPRIT, P1: Targeting Epigenetic Co-Activators of Ar with Small Molecule Inhibitors, $209,216; Liu, Zhi-Ping, CPRIT, AC: Epigenetic Mechanisms and Therapeutic Strategies for Targeting Prostate Cancer, $46,973; Luo, Weibo, CPRIT, The Role of Hypoxia-Inducible Factor 1 in Breast Cancer – Recruitment, $500,000; MacMillan, John, CPRIT, Natural Product for Treatment of Non Small Cell Lung Cancer, $255,039; Mangelsdorf, David, CPRIT, AC: Development of Nuclear Receptors and CoRegulators as Diagnostic and Therapeutic Targets in Breast and Lung Cancers, $56,143; Mason, Ralph, CPRIT, Noninvasive Identification of Prostate Tumor Hypoxia as a Prognostic Biomarker, $296,171; Mason, Ralph, CPRIT, P3: Effects of Hypoxia, $258,332;

McFadden, David, CPRIT, Deciphering Genetic and Epigenetic Mechanisms – Recruitment, $576,088; Millner, Lori, TX Higher Education Coordinating Bd, Applicant Awareness and Enrichment Program, $74,858; Minna, John, CPRIT, P1: Characterization of Nuclear Receptor and Co-Regulator Expression and Function in Lung Cancers, $411,517; Morrison, Sean, CPRIT, Recruitment of Established Investigators, $2,000,000; Munshi, Nikhil, Burroughs Wellcome Fund, Genomic Approaches to Understanding Cis-Regulatory Architecture of Atrioventricular Node, $140,000; Nam, Yunsun, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $496,368;

Nicastro, Daniela, CPRIT, High-Resolution Visualization of Native, Dynamic DNA-Interacting Complexes Inside – Recruitment of Rising Stars, $559,525; O’Donnell-Mendell, Kathryn, LUNGevity Fdn, Dissecting Novel Mechanisms of Lung Cancer Pathogenesis, $100,000; Orth, Kim, CPRIT, A New Cancer Target: AMPylation Machinery, $100,000; Rizo-Rey, Jose, CPRIT, P3: Molecular and Structural Basis of Epigenetic Regulation of AR, $263,157; Saha, Debabrata, CPRIT, C3: Image Guided Irradiation of Small Animals, $181,242; Scaglioni, Pier, CPRIT, Mutant KRAS Reprograms Lipid Metabolism Exposing Beta-Oxidation as a Novel Therapy, $229,240; Scherer, Philipp, CPRIT, Endotrophin and the Obesity/Cancer Nexus: Role in Growth and Chemoresistance, $299,999; Sharma, Preeti, Cystic Fibrosis Fdn, Improving Newborn Screening Through Physician Access, $32,400;

Siegwart, Daniel, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $359,586; Skapek, Stephen, CPRIT, P2: High Throughput Screening for Sarcoma Cell Proliferation and Survival Factors, $283,568; Skapek, Stephen, CPRIT, AC: Molecularly Targeted Therapy for Soft Tissue Sarcoma in Texas, $135,968; Timmerman, Robert, CPRIT, AC: Exploiting Radiobiology of Stereotactic Ablative Radiotherapy for Lung Cancer, $62,095; Toprak, Erdal, Human Frontier Science Prgm, Revealing the Fundamental Limits of Cell Growth, $112,500; Tu, Benjamin, CPRIT, Evaluation of the Role of Tumor Suppressor Candidate NPRL2 in Cell Growth Control, $198,732; Wang, Richard, Burroughs Wellcome Fund, Akt-Mediated Regulation of Autophagy & Tumorigenesis through Formation of Beclin 1/Keratin Intermediate Filament Complex, $140,000;

Wang, Zhigao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $500,000; Westover, Kenneth, CPRIT, Structure-Guided Kinase Inhibitor Design for Cancer Therapy, $300,000; White, Michael, CPRIT, AC: Innate Immunity and Cancer, $78,947; Xie, Yang, CPRIT, C2: Biostatistics, Bioinformatics and Database Core, $149,988; Yu, Hongtao, CPRIT, P2: Mechanism and Inhibition of LSD1-Dependent Transcription of AR Target Genes in Prostate Cancer Cells, $286,915;

Zhang, Chengcheng, CPRIT, Novel Targets for Acute Myeloid Leukemia Treatment, $300,000; Zhang, Xuewu, CPRIT, Analyses of Regulatory Mechanisms of Tankyrase, $292,552; Zhong, Qing, CPRIT, Dissecting a Necrotic Signaling Pathway in Human Cancer Cells, $100,000; Zhu, Hao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $573,685; Zhu, Hao, Burroughs Wellcome Fund, Investigating Lin28/let-7 Pathway in Mouse Models of Liver Cancer and Regeneration, $160,000.

Industry Sponsored Awards

(Dollar Amounts Not Available)

Bird, John, Study of Viaskin Milk for Treating IgE-Mediated Cow's Milk Allergy in Children (MILES study), INC Research; Brekken, Rolf, Determine Efficacy of HIF-2a Inhibition in Preclinical Models of NSCLC for Anti-Angiogenic Resistance, Peloton Therapeutics; Corey, David, Activation of Gene Expression, Rana Therapeutics; Courtney, Kevin, Phase 2 Study of Enzalutamide and P13 Kinase/mTOR Inhibitor LY3023414 in Men with Metastatic Castration Resistant Prostate Cancer, SCRI Development Innovations; Cripps, Michael, In Vitro Effects of QuikClot Hemostatic Dressing on Anticoagulated Blood, Z-Medica; Drazner, Mark, Targeting Acute Congestion with Tolvaptan in Congestive Heart Failure (TACTICS-HF), Duke Clin Res Inst; Gerber, David, Phase 2 Study of TH-4000 in Pts with eGFR-Mutant, T790M-Neg, Adv Non-Small Lung Cancer, Criterium;

Jain, Mamta, Phase 3 Study of MK1439A Once-Daily vs. ATRIPLA Once-Daily for Treatment-Naive HIV-1 Sbjs, DrugDev; Khan, Saad, Phase 3 Trial of Pembrolizumab (MK-3475) for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Merck Sharp & Dohme; Lea, Jayanthi, Phase 3 Trial of Maintenance FANG for High Risk Stage III/IV Ovarian Cancer, Clinipace Worldwide; Lingvay, Ildiko, Dose-Finding of Semaglutide Administered Subcutaneously, Novo Nordisk; Lotan, Yair, Multi-Institutional Study to Evaluate Molecular Staging Biomarkers in Pts Diagnosed with Bladder Cancer, Genomedx Biosciences;

Maher, Elizabeth, Phase 1 Study of Orally Admin AG-881 in Pts with Advanced Solid Tumors with IDH1 and/or IDH2 Mutation, Novella Clin; Matevosyan, Karen, Evaluation of the AMICUS Red Blood Cell Exchange (RBCx), Fenwal; McCavit, Timothy, Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC); Phase 3, Mast Therapeutics; McKnight, Steven, Study of Existing and New Chemicals that Stimulate the Salvage of NAD from Nicotinamide, Calico Life Sciences; Timmerman, Robert, AANS and ASTRO National Stereotactic Radiosurgery Quality Registry Plan, Quintiles; Unger, Roger, Studies to Establish Site of Action of SGLT2 Inhibitors in Type 2 Diabetes, Astrazeneca Pharma; Welch, Robert, Comparison of RTG Screws with Buttress Screws in Cadaveric Bone, SMV Scientific.