Publications for Xuewu Zhang, Ph.D.

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Featured Publications

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.

Shang G, Zhang C, Chen ZJ, Bai XC, Zhang X, Nature 2019 03 567 7748 389-393

Regulation of tankyrase activity by a catalytic domain dimer interface.

Fan C, Yarravarapu N, Chen H, Kulak O, Dasari P, Herbert J, Yamaguchi K, Lum L, Zhang X Biochem. Biophys. Res. Commun. 2018 09 503 3 1780-1785

Structural analyses of FERM domain-mediated membrane localization of FARP1.

Kuo YC, He X, Coleman AJ, Chen YJ, Dasari P, Liou J, Biederer T, Zhang X Sci Rep 2018 Jul 8 1 10477

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor.

Wu X, Zhang LS, Toombs J, Kuo YC, Piazza JT, Tuladhar R, Barrett Q, Fan CW, Zhang X, Walensky LD, Kool M, Cheng SY, Brekken R, Opferman JT, Green DR, Moldoveanu T, Lum L Nat. Cell Biol. 2017 Oct 19 10 1226-1236

Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling.

Qi N, Shi Y, Zhang R, Zhu W, Yuan B, Li X, Wang C, Zhang X, Hou F Nat Commun 2017 Jun 8 15676

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.

Shang G, Brautigam CA, Chen R, Lu D, Torres-Vázquez J, Zhang X Elife 2017 May 6

In Vitro Assay for the Rap GTPase-Activating Protein Activity of the Purified Cytoplasmic Domain of Plexin.

Pascoe HG, Wang Y, Zhang X Methods Mol. Biol. 2017 1493 107-118

Regulation of Plexin: A Ring of Structural Twists and Turns.

Kuo YC, Zhang X, Neuron 2016 Aug 91 3 497-9

Plexins function in epithelial repair in both Drosophila and zebrafish.

Yoo SK, Pascoe HG, Pereira T, Kondo S, Jacinto A, Zhang X, Hariharan IK Nat Commun 2016 7 12282

Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.

Pascoe HG, Gutowski S, Chen H, Brautigam CA, Chen Z, Sternweis PC, Zhang X Proc. Natl. Acad. Sci. U.S.A. 2015 Dec 112 48 14852-7

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