Featured Publications

NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways.

Udden SMN, Peng L, Gan JL, Shelton JM, Malter JS, Hooper LV, Zaki MH Cell Rep 2017 Jun 19 13 2756-2770

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.

Hu S, Peng L, Kwak YT, Tekippe EM, Pasare C, Malter JS, Hooper LV, Zaki MH Cell Rep 2015 Dec 13 9 1922-36

Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection.

Zaki MH, Man SM, Vogel P, Lamkanfi M, Kanneganti TD Proc. Natl. Acad. Sci. U.S.A. 2014 Jan 111 1 385-90

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

Zaki MH, Vogel P, Malireddi RK, Body-Malapel M, Anand PK, Bertin J, Green DR, Lamkanfi M, Kanneganti TD Cancer Cell 2011 Nov 20 5 649-60

The Nlrp3 inflammasome: contributions to intestinal homeostasis.

Zaki MH, Lamkanfi M, Kanneganti TD Trends Immunol. 2011 Apr 32 4 171-9

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD Immunity 2010 Mar 32 3 379-91

Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate.

Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, Akaike T Nat. Chem. Biol. 2007 Nov 3 11 727-35

Inflammatory Proteomic Network Analysis of Statin-treated and Lipopolysaccharide-activated Macrophages

Kamal AHM, Chakrabarty JK, Udden SMN, Zaki MH, Chowdhury SM Scientific Reports 2018 164 8

The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defense

Rajalakshmi A. Ramachandran, Christopher Lupfer and Hasan Zaki Advances in Microbial Physiology 2018 In press

Changes in the Dielectric Spectra of Murine Colon During Neoplastic Progression

Ahmet C. Sabuncu, Jeanne Shen, Md. Hasan Zaki, Ali Beskok Biomed. Phys. Eng. Express 2018