Recent study discovers NOD2 as a critical player in suppressing colorectal tumorigenesis

Published this summer in Cell Reports, research showed that NOD2, a gene associated with many inflammatory diseases, has a key role in suppressing colorectal tumorigenesis. This paper sheds light to a mechanistic view of NOD2-mediated regulation of intestinal inflammation and tumorigenesis.

NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways