Publications

Publications

    • Hanna-Addams, S and Wang, Z. (2018). Use of two-dimensional semi-denaturing detergent agarose gel electrophoresis to confirm size heterogeneity of amyloid or amyloid-like fibers, J Vis Exp (134), e57498, doi:10.3791/57498.

Mechanisms of necroptosis pathway research

    • Reynoso, E, Liu, H, Li, L, Yuan, A, Chen, S and Wang, Z (2017). Thioredoxin 1 actively maintains the pseudokinase MLKL in a reduced state to suppress MLKL polymerization and necroptosis. J Biol Chem 292, 17514-17524
    • Liu, S, Liu, H, Johnston, A, Hanna-Addams, S, Reynoso, E, Xiang, Y and Wang, Z. (2017). MLKL forms disulfide bond-dependent amyloid-like polymers to induce necroptosis. Proc Natl Acad Sci U S A , E7450-7459.
    • Hanus, J, Zhang, H, Wang, Z, Liu, Q Zhou, Q and Wang, S. (2013). Induction of necrotic cell death by oxidative stress in retinal pigment epithelial cells. Cell Death Dis 4: e965.
    • Wang, Z., Jiang, H., Chen, S., Du, F. and Wang, X. (2012). The mitochondrial phosphatase PGAM5 functions at the convergent point of multiple necrotic death pathways. Cell. 148(1-2):228-43. (Commented in 148(1-2):17-8. and evaluated in Faculty of 1000. F1000.com/13861956)
    • Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X. and Wang, X. (2012). Mixed Lineage kinase domain-like protein mediates necrosis signaling downstream of receptor-interacting serine-threonine kinase 3. Cell. 148(1-2):213-27. (Commented in Cell. 148(1-2):17-8., and evaluated in Faculty of 1000. F1000.com/14267354)
    • Wang, J., Li, A., Wang, Z., Feng, X., Olson, E.N., and Schwartz, R.J. (2007). Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts. Mol Cell Biol 27, 622-632.
    • Xing, W., Zhang, T.C., Cao, D., Wang, Z., Antos, C.L., Li, S., Wang, Y., Olson, E.N., and Wang, D.Z. (2006). Myocardin induces cardiomyocyte hypertrophy. Circ Res 98, 1089-1097.
    • Cao, D.*, Wang, Z.*, Zhang, C.L.*, Oh, J., Xing, W., Li, S., Richardson, J.A., Wang, D.Z., and Olson, E.N. (2005). Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol 25, 364-376. (* equal contribution).
    • Liu, Z.P., Wang, Z., Yanagisawa, H., and Olson, E.N. (2005). Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. Dev Cell 9, 261-270.
    • Oh, J.*, Wang, Z.*, Wang, D.Z.*, Lien, C.L., Xing, W., and Olson, E.N. (2004). Target gene-specific modulation of myocardin activity by GATA transcription factors. Mol Cell Biol 24, 8519-8528. (* equal contribution).­
    • Wang, Z., Wang, D.Z., Hockemeyer, D., McAnally, J., Nordheim, A., and Olson, E.N. (2004). Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature 428, 185-189.
    • Li, S., Wang, D.Z., Wang, Z., Richardson, J.A., and Olson, E.N. (2003). The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A 100, 9366-9370.
    • Wang, Z., Wang, D.Z., Pipes, G.C., and Olson, E.N. (2003). Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A 100, 7129-7134.
    • Wang, D.Z., Li, S., Hockemeyer, D., Sutherland, L., Wang, Z., Schratt, G., Richardson, J.A., Nordheim, A., and Olson, E.N. (2002). Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A 99, 14855-14860.
    • Wang, D.Z., Chang, P.S., Wang, Z., Sutherland, L., Richardson, J.A., Small, E., Krieg, P.A., and Olson, E.N. (2001). Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105, 851-862.