Skin cancer constitutes the most common group of malignancies in humans. Our research focuses on the pathogenesis of skin cancer development and the conserved signaling pathways underlying them.
We use a wide range of molecular techniques on cell culture, mouse models, and patient samples to explore three areas:
- The role of autophagy, a conserved cellular catabolic pathway, in skin biology and the pathogenesis of squamous cell carcinoma.
- The regulation of glucose transport in the skin and its role in skin development and tumorigenesis.
- The contribution of cutaneous polyomaviruses (MCPyV, TSPyV, HPyV6, and HPyV7) to infectious and neoplastic skin diseases.