Research Overview

Skin cancer constitutes the most common group of malignancies in humans. Our research focuses on the pathogenesis of skin cancer development and the conserved signaling pathways underlying them.

We use a wide range of molecular techniques on cell culture, mouse models, and patient samples to explore three areas:

  • The role of autophagy, a conserved cellular catabolic pathway, in skin biology and the pathogenesis of squamous cell carcinoma.
  • The regulation of glucose transport in the skin and its role in skin development and tumorigenesis.
  • The contribution of cutaneous polyomaviruses (MCPyV, TSPyV, HPyV6, and HPyV7) to infectious and neoplastic skin diseases.