Our research focuses on how the conserved signaling pathways that underlie normal skin development are altered during the development of non-melanoma skin cancers and inflammatory skin disease. We study these questions in cell culture, mouse models, and patient samples. Specific areas of interest include:
- The regulation of glucose transport and metabolism in normal skin and how it is altered in inflammatory and hyperproliferative skin diseases.
- The contribution of human papillomaviruses (HPVs) and cutaneous polyomaviruses (MCPyV, TSPyV, HPyV6, and HPyV7) to infectious and neoplastic skin diseases.