Publications

Publications

Peer-Reviewed Publications

Liu Z, Mar KB, Hanners NW, Perelman SS, Kanchwala M, Xing C, Schoggins JW, Alto NM.
A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB.
Nature. 2019 Apr;568(7751):249-253.

Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A.
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape. 
Nat Immunol. 2019 Apr;20(4):493-502. 

Richardson RB, Ohlson MB, Eitson JL, Kumar A, McDougal MB, Boys IN, Mar KB, De La Cruz-Rivera PC, Douglas C, Konopka G, Xing C, Schoggins JW.
A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication.
Nat Microbiol. 2018 Nov;3(11):1214-1223.

Mar KB, Rinkenberger NR, Boys IN, Eitson JL, McDougal MB, Richardson RB, Schoggins JW.
LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step.
Nat Commun. 2018 Sep 6;9(1):3603.

Rinkenberger N, Schoggins JW.
Mucolipin-2 Cation Channel Increases Trafficking Efficiency of Endocytosed Viruses.
MBio. 2018 Jan 30;9(1)

De La Cruz-Rivera PC, Kanchwala M, Liang H, Kumar A, Wang LF, Xing C, Schoggins JW.
The IFN Response in Bats Displays Distinctive IFN-Stimulated Gene
Expression Kinetics with Atypical RNASEL Induction.
J Immunol. 2018 Jan 1;200(1):209-217. 

Rosenberg BR, Freije CA, Imanaka N, Chen ST, Eitson JL, Caron R, Uhl SA, Zeremski M, Talal A, Jacobson IM, Rice CM, Schoggins JW.
Genetic Variation at IFNL4 Influences Extrahepatic Interferon-Stimulated Gene Expression in Chronic HCV Patients.
J Infect Dis. 2018 Jan 30;217(4):650-655.

Lipovsky A, Erden A, Kanaya E, Zhang W, Crite M, Bradfield C, MacMicking J, DiMaio D, Schoggins JW, Iwasaki A.
The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry.
J  Gen Virol. 2017 Nov;98(11):2821-2836.

Perelman SS, Abrams ME, Eitson JL, Chen D, Jimenez A, Mettlen M, Schoggins JW, Alto NM.
Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection.
PLoS Pathog. 2016 Dec 21;12(12):e1006102.

Kane M, Zang TM, Rihn SJ, Zhang F, Kueck T, Alim M, Schoggins J, Rice CM, Wilson SJ, Bieniasz PD.
Identification of Interferon-Stimulated Genes with Antiretroviral Activity.
Cell Host Microbe. 2016 Sep 14;20(3):392-405. 

Hanners NW, Eitson JL, Usui N, Richardson RB, Wexler EM, Konopka G, Schoggins JW.
Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with  Partial Cytopathic and Limited Immunogenic Effects.
Cell Rep. 2016 Jun 14;15(11):2315-22.

Feenstra B, Pasternak B, Geller F, Carstensen L, Wang T, Huang F, Eitson JL, Hollegaard MV, Svanström H, Vestergaard M, Hougaard DM, Schoggins JW, Jan LY, Melbye M, Hviid A. Common variants associated with general and MMR vaccine-related febrile seizures.
Nat Genet. 2014 Dec;46(12):1274-82.

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity.
Schoggins JW, MacDuff DA, Imanaka N, Gainey MD, Shrestha B, Eitson JL, Mar KB, Richardson RB, Ratushny AV, Litvak V, Dabelic R, Manicassamy B, Aitchison JD, Aderem A, Elliott RM, García-Sastre A, Racaniello V, Snijder EJ, Yokoyama WM, Diamond MS, Virgin HW, Rice CM.
Nature. 2014 Jan 30;505(7485):691-5.

MX2 is an interferon-induced inhibitor of HIV-1 infection.
Kane M, Yadav SS, Bitzegeio J, Kutluay SB, Zang T, Wilson SJ, Schoggins JW, Rice CM, Yamashita M, Hatziioannou T, Bieniasz PD.
Nature. 2013 Oct 24;502(7472):563-6.

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage.
Cheon H, Holvey-Bates EG, Schoggins JW, Forster S, Hertzog P, Imanaka N, Rice CM, Jackson MW, Junk DJ, Stark GR.
EMBO J. 2013 Oct 16;32(20):2751-63.

Inhibition of HIV-1 Particle Assembly by 2',3'-Cyclic-Nucleotide 3'-Phosphodiesterase.
Wilson SJ, Schoggins JW, Zang T, Kutluay SB, Jouvenet N, Alim MA, Bitzegeio J, Rice CM and Bieniasz P.
Cell Host and Microbe, 12(4):585-97. 2012.

Dengue reporter viruses reveal viral dynamics in interferon receptor deficient mice and sensitivity to interferon effectors in vitro.
Schoggins JW, Dorner M, Fuelner M, Imanaka N, Murphy MY, Ploss A, Rice CM.
Proc Natl Acad Sci U S A. 109(36):14610-5. 2012.

Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency.
Bogunovic D, Byun M, Abhyankar A, Durfee LA, Sanal O, Mansouri D, Grant A, Adimi P, Mansouri N,Okada S, Bryant V, Kong XF, Kreins A, Boisson B, Zadeh S, Darazam I, Schoggins JW, Rice CM, Al-Muhsen S, Bustamante, J, Huibregtse, JM, Abel L, Boisson-Dupuis S, Casanova J-L.
Science. 337(6102):1684-8. 2012.

Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-Alphavirus activity.
Karki S, Li M, Schoggins JW, Tian S, Rice CM, and MacDonald MR.
PlosONE. 7(5):e37398. 2012.

C7L family of poxvirus host-range genes inhibit antiviral activities induced by type I interferons and interferon regulatory factor1.
Meng X, Schoggins JW, Rose L, Cao J, Rice CM and Xiang Y.
J. Virol. 86(8):4538-47, 2012.

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.
Andrus M, Marukian S, Jones CT, Catanese MT, Sheahan TP, Schoggins JW, Barry WT, Dustin LB, Trehan K, Ploss A, Bhatia SN and Rice CM.
Hepatology. 54(6):1901-12, 2011.

A genetically humanized mouse model for hepatitis C virus infection.
Dorner M, Horwitz JA, Robbins JB, Barry WT, Feng Q, Mu K, Jones CT, Schoggins JW, Catanese MT, Burton DR, Law M, Rice CM, Ploss A.
Nature. 2011 Jun 8;474(7350):208-11.

A diverse array of gene products are effectors of the type I interferon antiviral response.
Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, Rice CM.
Nature. 472:481-5, 2011.

Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry.
Kohaar I, Ploss A, Korol E, Mu K, Schoggins JW, O’Brien TR, Rice CM, Prokunina-Olsson L.
J. Virol. 84(14):6987-94, 2010.

Real-time imaging of hepatitis C virus using a fluorescent cell-based reporter system.
Jones CT, Catanese MT, Law LMJ, Khetani S, Syder AJ, Ploss A, Oh TS, Schoggins JW, MacDonald MR, Bhatia SN, Rice CM.
Nature Biotech. 28(2):167-71, 2010.

Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber.
Schoggins JW and Falck-Pedersen E. 
Virology. 395(1):10-20, 2009.

Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells.
Diaz F, Gravotta D, Deora A, Schreiner R, Schoggins J, Falck-Pedersen E, Rodriguez-Boulan E.
Proc Natl Acad Sci U S A. 106(27):11143-8, 2009.

Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator.
Nociari M, Ocheretina O, Schoggins JW, and Falck-Pedersen E.
J. Virol. 81(8):4145-57, 2007.

Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity.
Schoggins JW and Falck-Pedersen E.
J. Virol. 80(21):10634-44, 2006.

Influence of fiber detargeting on adenovirus mediated innate and adaptive immune activation.
Schoggins JW, Nociari M, Philpott N, and Falck-Pedersen E.
J. Virol. 79(18): 11627-37, 2005.

Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo.
Schoggins JW, Gall JG, and Falck-Pedersen E.
J Virol. 77(2):1039-48, 2003.

Coordinated regulation of secretory phospholipase A2 and cyclooxyganese-2 in activated human keratinocytes.
Rys-Sikora KE, Konger RL, Schoggins JW, Malaviya R, and Pentland AP.
Am. J. Phys.-Cell Phys. 278: C822-33, 2000.  

Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition.
Pentland AP, Schoggins JW, Scott GA, Khan KNM, and Han R.
Carcinogenesis. 20(10): 1939-44, 1999.  1939-44, 1999. 

 

Reviews, Chapters, Commentaries

Recent advances in antiviral interferon-stimulated gene biology.
Schoggins JW.
F1000Res. 2018 Mar 12;7:309.

NLRX1 Helps HIV Avoid a STING Operation.
Mar KB, Schoggins JW.
Cell Host Microbe. 2016 Apr 13;19(4):430-1.

A phospholipase linkAGE to SARS susceptibility.
Schoggins JW.
J Exp Med. 2015 Oct 19;212(11):1755.

IMMUNOLOGY. Viruses carry antiviral cargo.
Schoggins JW.
Science. 2015 Sep 11;349(6253):1166-7.

A Sense of Self: RIG-I's Tolerance to Host RNA.
Schoggins JW.
Immunity. 2015 Jul 21;43(1):1-2.

Interferon-stimulated genes: roles in viral pathogenesis.
Schoggins JW.
Curr Opin Virol. 2014 Jun;6:40-6.

Lipids in innate antiviral defense.
Schoggins JW, Randall G.
Cell Host Microbe. 2013 Oct 16;14(4):379-85.

Regulating interferon antiviral activity: a role for epidermal growth factor receptor.
Schoggins JW.
Hepatology. 2013 Oct;58(4):1200-2.

Host restriction factor screening: let the virus do the work.
Diamond MS, Schoggins JW.
Cell Host Microbe. 2013 Sep 11;14(3):229-31.

Innate immune responses to hepatitis C virus.
Schoggins JW, Rice CM.
Curr Top Microbiol Immunol. 2013;369:219-42.

Interferon-stimulated genes and their antiviral effector functions.
Schoggins JW and Rice CM.
Current Opinion in Virology. 1(6):519-525. 2011. 

Adenovirus capsid chimeras: fiber terminal exon insertions/gene replacements in the major late transcription unit.
Gall J, Schoggins J, Falck-Pedersen E.
Methods Mol Med. 130:107-23. 2007.