G protein regulation
The Ross Lab has closed; Dr. Ross is now Associate Dean for Basic Research.
Elliott M. Ross, Ph.D.
Professor, Department of Pharmacology
Associate Dean for Basic Research
Research Integrity Officer
UT Southwestern Medical Center
6001 Forest Park Road
Dallas, TX 75390-9041
USA
Telephone: (214) 645-6134
Inhibition of Brain Gz GAP and Other RGS Proteins by Palmitoylation of Protein α Subunits
Tu, Y., Wang, J., and Ross, E.M. November 1997 278 1132-1135Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP
Turcotte, M., Tang, W., Ross, E.M. August 2008 4 e100148Phospholipase C-β1 is a GTPase Activating Protein for Gq/11, its Physiologic Regulator
Berstein, G., Blank, J.L., Jhon, D-Y., Exton, J.H., Rhee, S.G., and Ross, E.M. August 1992 70 411-418Amino Acids Regulate mTORC1 by an Obligate Two-Step Mechanism.
Dyachok J, Earnest S, Iturraran EN, Cobb MH, Ross EM 2016 Sep J. Biol. Chem.Intrinsic PH Domain Motion in Phospholipase C-? Exposes a G?? Binding Site.
Kadamur G, Ross EM 2016 Mar J. Biol. Chem.WNK1 promotes PIP2 synthesis to coordinate growth factor and GPCR-Gq signaling.
An SW, Cha SK, Yoon J, Chang S, Ross EM, Huang CL 2011 Dec Curr. Biol. 23 21 1979-87Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins.
Mukhopadhyay S, Ross EM 1999 Aug Proc. Natl. Acad. Sci. U.S.A. 17 96 9539-44Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.
May DC, Ross EM, Gilman AG, Smigel MD 1985 Dec J. Biol. Chem. 29 260 15829-33Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells.
Wauson EM, Guerra ML, Dyachok J, McGlynn K, Giles J, Ross EM, Cobb MH 2015 Aug Mol. Endocrinol. 8 29 1114-1122Galpha(q) and phospholipase C-beta: turn on, turn off, and do it fast.
Ross EM 2011 Sci Signal 159 4 pe5Structural determinants for phosphatidic acid regulation of phospholipase C-beta1.
Ross EM, Mateu D, Gomes AV, Arana C, Tran T, Litosch I 2006 Nov J. Biol. Chem. 44 281 33087-94Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle.
Mukhopadhyay S, Ross EM 2002 Meth. Enzymol. 344 350-69RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20.
Barker SA, Wang J, Sierra DA, Ross EM 2001 Dec Genomics 3 78 223-9Reciprocal signaling between heterotrimeric G proteins and the p21-stimulated protein kinase.
Wang J, Frost JA, Cobb MH, Ross EM 1999 Oct J. Biol. Chem. 44 274 31641-7Kinetic control of guanine nucleotide binding to soluble Galpha(q).
Chidiac P, Markin VS, Ross EM 1999 Jul Biochem. Pharmacol. 1 58 39-48The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling.
Zeng W, Xu X, Popov S, Mukhopadhyay S, Chidiac P, Swistok J, Danho W, Yagaloff KA, Fisher SL, Ross EM, Muallem S, Wilkie TM 1998 Dec J. Biol. Chem. 52 273 34687-90Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits.
Tu Y, Wang J, Ross EM 1997 Nov Science 5340 278 1132-5Expression of human muscarinic cholinergic receptors in tobacco.
Mu JH, Chua NH, Ross EM 1997 May Plant Mol. Biol. 2 34 357-62Purification and characterization of phospholipase C-beta 1 mutants expressed in E. coli.
Meij JT, Ross EM 1996 Aug Biochem. Biophys. Res. Commun. 3 225 705-11Protein modification. Palmitoylation in G-protein signaling pathways.
Ross EM 1995 Feb Curr. Biol. 2 5 107-9G protein GTPase-activating proteins: regulation of speed, amplitude, and signaling selectivity.
Ross EM 1995 Recent Prog. Horm. Res. 50 207-21Gs regulation of endosome fusion suggests a role for signal transduction pathways in endocytosis.
Colombo MI, Mayorga LS, Nishimoto I, Ross EM, Stahl PD 1994 May J. Biol. Chem. 21 269 14919-23Regulation of G-protein activation by mastoparans and other cationic peptides.
Ross EM, Higashijima T 1994 Meth. Enzymol. 237 26-37GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes.
Strittmatter SM, Cannon SC, Ross EM, Higashijima T, Fishman MC 1993 Jun Proc. Natl. Acad. Sci. U.S.A. 11 90 5327-31Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator.
Berstein G, Blank JL, Jhon DY, Exton JH, Rhee SG, Ross EM 1992 Aug Cell 3 70 411-8Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells.
Parker EM, Kameyama K, Higashijima T, Ross EM 1991 Jan J. Biol. Chem. 1 266 519-27ATP-dependent regulation of flagellar adenylylcyclase in gametes of Chlamydomonas reinhardtii.
Zhang YH, Ross EM, Snell WJ 1991 Dec J. Biol. Chem. 34 266 22954-9Reconstitution of receptors and G proteins in phospholipid vesicles.
Cerione RA, Ross EM 1991 Meth. Enzymol. 195 329-42Signal sorting and amplification through G protein-coupled receptors.
Ross EM 1989 Aug Neuron 2 3 141-52Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists.
Pedersen SE, Ross EM 1985 Nov J. Biol. Chem. 26 260 14150-7