Featured Publications

Organization of Chromatin by Intrinsic and Regulated Phase Separation.

Gibson BA, Doolittle LK, Schneider MWG, Jensen LE, Gamarra N, Henry L, Gerlich DW, Redding S, Rosen MK, Cell 2019 Sep

Biomolecular condensates: organizers of cellular biochemistry.

Banani SF, Lee HO, Hyman AA, Rosen MK Nat. Rev. Mol. Cell Biol. 2017 Feb

Compositional Control of Phase-Separated Cellular Bodies.

Banani SF, Rice AM, Peeples WB, Lin Y, Jain S, Parker R, Rosen MK Cell 2016 Jul 166 3 651-63

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.

Pak CW, Kosno M, Holehouse AS, Padrick SB, Mittal A, Ali R, Yunus AA, Liu DR, Pappu RV, Rosen MK Mol. Cell 2016 Jul 63 1 72-85

Phase separation of signaling molecules promotes T cell receptor signal transduction.

Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD Science 2016 Apr 352 6285 595-9

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins.

Lin Y, Protter DS, Rosen MK, Parker R Mol. Cell 2015 Sep

Phase transitions of multivalent proteins can promote clustering of membrane receptors.

Banjade S, Rosen MK Elife 2014 Oct 3

Phase transitions in the assembly of multivalent signalling proteins.

Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK Nature 2012 Mar 483 7389 336-40

Mechanistic dissection of increased enzymatic rate in a phase-separated compartment.

Peeples W, Rosen MK, Nat Chem Biol 2021 Jun 17 6 693-702

The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.

Zhemkov V, Ditlev JA, Lee WR, Wilson M, Liou J, Rosen MK, Bezprozvanny I, Elife 2021 May 10