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Publications

Publications

Review Articles:

1. Oh DY, Jerrold M Olefsky. G Protein-Coupled Receptors as Targets for Anti-Diabetic Therapeutics. Nature Reviews Drug Discovery. 2016 Mar;15(3):161-172. [PubMed]

2. Oh DY, Walenta E. Omega-3 Fatty Acids and FFAR4. Frontiers in Endocrinology. 2014;5:115. doi:10.3389/fendo.2014.00115. [PubMed]

3. Oh DY, Walenta E. The Role of Omega-3 Fatty Acid Receptor GPR120 in Insulin Resistance. Int J Obes Supp 4 2014; 4:S14-S16 [PubMed]

4. Oh DY, Lagakos WS. The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity. Curr Opin Clin Nutr Metab Care2011; 14:322-327 [PubMed]

5. Oh DY, Kim K, Kwon HB, Seong JY. Cellular and molecular biology of orphan G protein-coupled receptors. International Review of Cytology2006; 252:95-150 [PubMed]

 

Perspective/Preview Articles: 

1. Oh DY, Olefsky JM. Omega-3 fatty acids and GPR120. Cell Metab 2012 May; 15:564- 565 [PubMed]

2. Oh DY, Olefsky JM. Wnt fans the flames in obesity. Science2010; 329:397-398 [PubMed]

 

Selected Research Articles:

1. Li P, Liu S, Lu M, et al. Hematopoietic-derived Galectin-3 Causes Cellular and Systemic Insulin Resistance. Cell. 2016;167(4):973-984.e12. doi:10.1016/j.cell.2016.10.025.[PubMed]

2. Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh DY*. Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice. Diabetes2015 Apr;64(4):1120-1130 * Corresponding Author [PubMed]

3. Li, P., Oh, D. Y., Bandyopadhyay, G., Lagakos, W. S., Talukdar, S., Osborn, O., … Olefsky, J. M. (2015). LTB4 causes macrophage–mediated inflammation and directly induces insulin resistance in obesity. Nature Medicine21(3), 239–247. http://doi.org/10.1038/nm.3800 [PubMed]

4. Oh DY*, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi T, Cox JM, Powels MA, Salvo JD, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, Mcnelis J, Bogner-Strauss JG, Olefsky JM. A Gpr120 Selective Agonist Improves Insulin Resistance and Chronic Inflammation.Nat Med2014 Aug;20(8):942-947 * Corresponding Author [PubMed]

5. Lee, YS, Kin JW, Osborn O, Oh DY, Schenk S, Sasik R, Chen A, Chung H, Murphy A, Watkins SM, Quehenberger O, Johnson RS, Olefsky JM. Increased Adipocyte O2Consumption Triggers HIF-1a Causing Inflammation and Insulin Resistance in Obesity. Cell2014 Jun 5;157(6):1339-1352 [PubMed]

6. Li, P., Spann, N. J., Kaikkonen, M. U., Lu, M., Oh, D. Y., Fox, J. N., … Olefsky, J. M. (2013). NCoR REPRESSION OF LXRs RESTRICTS MACROPHAGE BIOSYNTHESIS OF INSULIN-SENSITIZING OMEGA 3 FATTY ACIDS. Cell155(1), 200–214. http://doi.org/10.1016/j.cell.2013.08.054 [PubMed]

7. Talukdar S*, Oh DY*, Bandyopadhyay G, Xu J, McNelis J, Dongmei Li, Lu M, Li P, Ofrecio JM, Lin M, Brenner MB, Olefsky JM. Neutrophils mediate insulin resistance in high fat diet fed mice via secreted elastase. Nat Med2012 Sep;18(9):1407-1412 * Co-first Author [PubMed] 

8. Osborn O, Oh DY, Thiede L, McNelis J, Morinaga H, Talukdar S, Lu M, Li P, Nalbandian S, Sanchez-Alavez M, HadcockJ, Bartfai T, Olefsky JM. Deletion of G protein coupled receptor 21 (Gpr21) improves insulin sensitivity in diet-induced obese mice. J Clin Invest 2012 Jul 2;122(7):2444-2453 [PubMed]

9. Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. Increased macrophage migration into adipose tissue in obese mice. Diabetes2012 Feb;61(2):346-354 [PubMed]

10. Oh DY, Talukdar S, Bae EJ, Imamura T, Fan W, Morinaga H, Li P, Lu WJ, Watkins SM, Olefsky JM. GPR120 is an Omega-3 polyunsaturated fatty acid receptor and mediates potent anti-inflammatory and insulin sensitizing effects. Cell2010 Sep 3; 142(5):687-698 [PubMed]

 

Full list of publications can be found on PubMed